Protein Alignment pnut and SEPTIN6

DIOPT Version :10

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_011529619.1
• Gene: SEPTIN6 / 23157
• HGNCID: 15848
• Length: 526
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 162/437 - (37%)
• Similarity: 262/437 - (59%)
• Gaps: 34/437 - (7%)

  Fly   115 KPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYNAEQYPGPSLR 179
            :.:.:||:|||.:||:|:..|:|.:||.|.::.||.:|||||||::::|     |.:....|:..
Human    15 RTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLF-----NTKFEGEPATH 74

  Fly   180 KKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRVYR- 243
            .:..|.:::....|:|:.|.|.||:|.|.||||.::..:.:.||:|::|:::|.||..|.::.|
Human    75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRV 139

  Fly   244 -KTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNE 307
             .|..|||:|.|||||||:||.|..||:..|:.|..|||::|:|||||.::..|:..||.:|.:|
Human   140 LHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSE 204

  Fly   308 IAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIEQDGKKVRGRRYPWGLVEVENL 372
            :..:.::||.||...|..||...|   :.:.:||||:|:...::...|.:|.|:||||.|:|||.
Human   205 LVSNGVQIYQFPTDDESVAEINGT---MNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQVENE 266

  Fly   373 THCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGLVDGKARLSNKNPLTQME--EEKR 435
            .||||:.||.|:||.:::||::.|:..|||.||..||.|:|..|..   .:..|.:..|  |.||
Human   267 AHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD---PDSKPFSLQETYEAKR 328

  Fly   436 -EHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRELEEKRREFEREK 499
             |...:::|.|.||.|:|..:||||..:|:::|.||..:.:..||..:.:.::||:|::..:
Human   329 NEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLD--- 390

  Fly   500 KEWEDVNHVTLEELKRRSLGA---NSSTDNVDG----KKEKKKKGLF 539
               ::||     ..|:|...|   .|......|    |::|:||..:
Human   391 ---DEVN-----AFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNSY 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	3a0901s04IAP86	58..>210	CDD:273381	34/94 (36%)
		Septin	140..411	CDD:395596	113/272 (42%)
		UDM1_RNF168	427..484	CDD:409018	21/59 (36%)
SEPTIN6	XP_011529619.1	CDC_Septin	39..307	CDD:206649	114/275 (41%)