Protein Alignment pnut and unc-61

DIOPT Version :9

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_872156.2
• Gene: unc-61 / 179976
• WormBaseID: WBGene00006795
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 159/462 - (34%)
• Similarity: 257/462 - (55%)
• Gaps: 54/462 - (11%)

  Fly    60 PPNQPPSVPVAASGKLDTSGGGASNGDSNKLTHD------LQEKEHQQAQKPQKP-------PLP 111
            ||:|||. ||             .:...|:.||:      ............:||       |.|
 Worm    81 PPHQPPP-PV-------------PHHHQNQPTHNNTTTISSATSSINTTTTSKKPTIAAPTAPSP 131

  Fly   112 VRQ------KPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYNA 170
            ::.      :.|::.|:|||.:||:|:.:|||:.||:|.||.||.:|.||:|||.|:|     |.
 Worm   132 IKSLSDHTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLF-----NM 191

  Fly   171 EQYPGPSLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYL 235
            :....|...:.|||.:......:.|.|:.:.|.:|:|.||||.:|.......|::|::|::|.||
 Worm   192 KLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYL 256

  Fly   236 TAESRVYR--KTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVH 298
            ..|.:..|  :..:|||:|.|||||:|:||||..||:..::.|:.:||::|||||:||...||:.
 Worm   257 QEELKPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDELL 321

  Fly   299 LFKKQILNEIAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGA-NTIIEQDGKKVRGRRY 362
            .||.:||:|:...||.||.||.   |....:.|.:.:...|||||||: :.:.:::|:.||.|:|
 Worm   322 RFKAKILSELKSQKIDIYTFPT---DDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRARQY 383

  Fly   363 PWGLVEVENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGLVDGKARLSNKNPL 427
            |||:|||||.:||||:.||..::||::.:::..|:...|||||..:|.::.:.||:   :....:
 Worm   384 PWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGE---TGPKII 445

  Fly   428 TQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEE-------RKKALELQI 485
            .::.::.|||:.:..:.|..:.:.|..|:......:|..|..||.|..|       ....|:::|
 Worm   446 EKLAQKHREHQDEFSRRELTLREEFQKKLDVTEGDMRKVEEGLAAREREVHENYNREASKLDMEI 510

  Fly   486 RELEEKR 492
            |:|.|:|
 Worm   511 RQLTEER 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	CDC3	121..482	CDD:227352	138/370 (37%)
		Septin	139..411	CDD:279124	114/274 (42%)
unc-61	NP_872156.2	CDC_Septin	165..434	CDD:206649	114/276 (41%)
		DUF5401	<380..530	CDD:375164	45/141 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.950