Protein Alignment pnut and unc-59

DIOPT Version :9

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_493388.1
• Gene: unc-59 / 173233
• WormBaseID: WBGene00006793
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 206/457 - (45%)
• Similarity: 274/457 - (59%)
• Gaps: 62/457 - (13%)

  Fly   118 EIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYN------AEQYPGP 176
            |...|.||||.||||:|:|||.||:|||||||.|||||||.||::||::|.|      |..:|.|
 Worm    23 ENPNYWGFANFPNQVFRRAVKNGFDFTLMVVGRSGLGKSTFINTLFLAEINNLNEKESAPTHPHP 87

  Fly   177 SLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRV 241
            |     ||.||...|.|.||.|:|.||:||||||||||:||.||.||:.||:||:.|....|:|:
 Worm    88 S-----TVRVEEKLVKLVENSVSLNLTLVDTPGFGDAVNNSKCWEPIVNYVESKFFEQFCEETRI 147

  Fly   242 YR-KTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQIL 305
            .| :.|.|..||.|||||.||||||.|:||..|:.|..:||:||||:|||.:|.||:..|||||:
 Worm   148 DRGEKIVDKCVHLCLYFIEPSGHGLKPIDIELMKHLHGRVNIVPVISKADCLTRDELLRFKKQIV 212

  Fly   306 NEIAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIEQDGKKVRGRRYPWGLVEVE 370
            .:....:||:|.|| .|||...:....:.||..:|||::|:|.:.|:||||:|.|.||||.||||
 Worm   213 KDAETAEIKLYKFP-ELEDPYTDKVAIEKLRKALPFAIIGSNMLKEKDGKKIRYREYPWGTVEVE 276

  Fly   371 NLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGLVDGKARLSNKNPLTQMEEEKR 435
            |:.|.||:.||:|:|||:|.|:.|||.||||||:|.|::.  ||...:   .|::|.|.:|||:|
 Worm   277 NMQHNDFLTLRDMIIRTNLIDMIDVTRNVHYENFRFRQME--GLPKNE---KNRDPFTHLEEERR 336

  Fly   436 EHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRELEE--------KR 492
            :.||.:.:....:|:||..|...:           .:|.:||..|||    |||:        ||
 Worm   337 QKEQDLDEKRNTLEKVFTEKTSAR-----------KKRSDERMSALE----ELEQQNKQKIDAKR 386

  Fly   493 REFEREKKE------------------WEDVNH---VTLEELKRRSLGANSSTDNVDGKKEKKKK 536
            .|..|.:.|                  :.:.||   .||....:.|....|:|.:..|..:|:..
 Worm   387 AEIIRLRHEISELKNGNLTSSQTSLAMYNENNHSQNSTLNSTTKSSPPPTSATSSSSGTMKKRMG 451

  Fly   537 GL 538
            ||
 Worm   452 GL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	CDC3	121..482	CDD:227352	184/367 (50%)
		Septin	139..411	CDD:279124	152/278 (55%)
unc-59	NP_493388.1	CDC_Septin	44..318	CDD:206649	152/281 (54%)
		DUF4200	328..>401	CDD:372763	25/87 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165281
Domainoid	1	1.000	294	1.000	Domainoid score	I811
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1354
Inparanoid	1	1.050	353	1.000	Inparanoid score	I1324
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51878
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	1	1.000	-	-		otm14281
orthoMCL	1	0.900	-	-		OOG6_104146
Panther	1	1.100	-	-	LDO	PTHR18884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	1	1.000	-	-		X204
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840