Protein Alignment pnut and SEPTIN12

DIOPT Version :10

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_016878427.1
• Gene: SEPTIN12 / 124404
• HGNCID: 26348
• Length: 364
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 128/285 - (44%)
• Similarity: 189/285 - (66%)
• Gaps: 12/285 - (4%)

  Fly   149 GASGLGKSTLINSMFLSDIYNAEQYPGPSLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDA 213
            |.|||||||::|::|.|.::.:.. ||..:...:|:.:.:...:::|.||.|.|||.|||||||.
Human    62 GQSGLGKSTMVNTLFKSKVWKSNP-PGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQ 125

  Fly   214 VDNSNCWVPILEYVDSKYEEYLTAESRVYR-KTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLS 277
            ::|.|||.|||.|::.:||:||..|..:.| :.|.|:|||||:||:.|:||.|.||||..:|.|.
Human   126 INNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLC 190

  Fly   278 DKVNLVPVIAKADTMTPDEVHLFKKQILNEIAQHKIKIYD---FPATLEDAAEEAKTTQNLRSRV 339
            ..||:|||||:||::|.:|...|:::|...:..|.|.:|.   |...:.|....:|    ||.|:
Human   191 RTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSK----LRDRI 251

  Fly   340 PFAVVGANTIIEQDGKKVRGRRYPWGLVEVENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENY 404
            |||||||:.....:|:.|.||:..||::||||:.||:|..||:::||:|||||||:|:|:|||||
Human   252 PFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENY 316

  Fly   405 RCRKLSELGLV---DGKARLSNKNP 426
            |..:|:|..|:   .|...|:..:|
Human   317 RVIRLNESHLLPRGPGWVNLAPASP 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	3a0901s04IAP86	58..>210	CDD:273381	24/60 (40%)
		Septin	140..411	CDD:395596	123/265 (46%)
		UDM1_RNF168	427..484	CDD:409018	128/285 (45%)
SEPTIN12	XP_016878427.1	CDC_Septin	62..323	CDD:206649	123/265 (46%)