Protein Alignment pnut and septin2

DIOPT Version :10

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001090723.1
• Gene: septin2 / 100036706
• XenbaseID: XB-GENE-480201
• Length: 355
• Species: Xenopus tropicalis
• Alignment Length: 355
• Identity: 181/355 - (50%)
• Similarity: 250/355 - (70%)
• Gaps: 19/355 - (5%)

  Fly   100 QQAQ--KPQKPPLPVRQKPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSM 162
            ||||  .|:.|            ||||||||||||:||:|::||||||||||.|||||||||||:
 Frog     4 QQAQFTNPETP------------GYVGFANLPNQVHRKSVRKGFEFTLMVVGESGLGKSTLINSL 56

  Fly   163 FLSDIYNAEQYPGPSLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYV 227
            ||:|:|.....||.:.:.::||.:||:.|.::|.||.|.||||||||:|||::..:|:.||:.||
 Frog    57 FLTDLYPERVVPGAADKIERTVEIEASTVEIEERGVKLRLTVVDTPGYGDAMNCVDCFKPIISYV 121

  Fly   228 DSKYEEYLTAESRVYRKTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTM 292
            |:::|.||..||.:.|:.|.|:|||||.|||:|.||||.|||:..|::|.:|||:|||||||||:
 Frog   122 DNQFERYLHDESGLNRRHIVDNRVHCCFYFISPFGHGLKPLDVEFMKALHNKVNIVPVIAKADTL 186

  Fly   293 TPDEVHLFKKQILNEIAQHKIKIYDFPATLEDAAEEAK-TTQNLRSRVPFAVVGANTIIEQDGKK 356
            |..|....|:::|:||.:|.||||..|....|..|:.| .|:.|::.:||.|||:|.:||..|||
 Frog   187 TLRERERLKRRVLDEIEEHGIKIYQLPDAESDEDEDFKEQTRLLKASIPFTVVGSNQLIEAKGKK 251

  Fly   357 VRGRRYPWGLVEVENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGLVD--GKA 419
            ||||.||||:|||||..|.||:.||.|:| ||:|||::||.::||||:|..:|.: |:..  ...
 Frog   252 VRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKK-GVASKVENV 314

  Fly   420 RLSNKNPLTQMEEEKREHEQKMKKMEAEME 449
            .::....|.:.|.|.|..::.:.:|:|:|:
 Frog   315 EVTKDQILQEKEAELRRMQEMIARMQAQMQ 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	3a0901s04IAP86	58..>210	CDD:273381	64/111 (58%)
		Septin	140..411	CDD:395596	152/271 (56%)
		UDM1_RNF168	427..484	CDD:409018	7/23 (30%)
septin2	NP_001090723.1	Septin	34..305	CDD:395596	152/271 (56%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	43..50		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	100..103		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	181..184		2/2 (100%)
		Important for dimerization. /evidence=ECO:0000250	259..269		7/9 (78%)