Protein Alignment dpn and Heyl

DIOPT Version :9

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_038933.2
• Gene: Heyl / 56198
• MGIID: 1860511
• Length: 326
• Species: Mus musculus
• Alignment Length: 384
• Identity: 99/384 - (25%)
• Similarity: 148/384 - (38%)
• Gaps: 122/384 - (31%)

  Fly    24 GSNGRMSNP------NGL------------SKAELRKTNKPIMEKRRRARINHCLNELKSLILEA 70
            ||:|....|      |.|            |:.:.||..:.|:|||||.|||..|:||:.|:..|
Mouse     9 GSDGESDGPIDVGQENDLSQMARPLTTPSPSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTA 73

  Fly    71 MKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMD 135
            .:|..:  :|||||::|:|||.||:.:..........:....|.....||.||..||.||:..::
Mouse    74 FEKQGS--SKLEKAEVLQMTVDHLKMLHASGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLE 136

  Fly   136 GIDT---GVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNN 197
            |..:   .||.||.:||...|..:|                 |:...|:|..  ||..|....:
Mouse   137 GPSSHADPVRIRLLSHLKSYAAEME-----------------PSPTTTSALA--FPVWPWSFLH- 181

  Fly   198 SRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPGSAAGVAAGTASAALASI 262
                 |.|     ||..:.|:|     |::       ...|||                 .|.||
Mouse   182 -----SCP-----GLPSLNSQL-----AIL-------GRVPGP-----------------VLPSI 207

  Fly   263 ANPTHLNDYTQSFRMSAFSKPVNT--SVPANLPENLIHTLPGQTQLPVKNSTSPPLSPISSISSH 325
            ::|.:               |::.  |.|.:.|..   |:|     |.:.:..|.....|:..:|
Mouse   208 SSPPY---------------PISALRSAPVHRPAG---TIP-----PTRRNLLPSRGVTSTQRAH 249

  Fly   326 CEESRAASPTVDVMSKHSFAGVFSTPP--PTSA----ETSFNTSGSLNLSAGSHDSSGC 378
            ..| |.|:|....:...:...:...||  ||:|    ::..|.|||:        ||.|
Mouse   250 LPE-RPAAPPPTALDARAARSIVPIPPCSPTTAPGAGKSDDNVSGSI--------SSPC 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	HLH	39..101	CDD:238036	28/61 (46%)
		ORANGE	114..158	CDD:128787	16/46 (35%)
Heyl	NP_038933.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		13/46 (28%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	42..111		28/70 (40%)
		HLH	44..100	CDD:238036	28/57 (49%)
		ORANGE	115..162	CDD:128787	17/63 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	223..260		11/45 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..306		12/36 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830924
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740