Protein Alignment dpn and hes1

DIOPT Version :10

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001011194.1
• Gene: hes1 / 496617
• XenbaseID: XB-GENE-487995
• Length: 267
• Species: Xenopus tropicalis
• Alignment Length: 264
• Identity: 109/264 - (41%)
• Similarity: 144/264 - (54%)
• Gaps: 44/264 - (16%)

  Fly    17 NGYSDSYGSNGRMSNPNGLSK--AELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHT 79
            |..|....:...|||.....|  :|.||::|||||||||||||..|.:||:|||:|:|||.:||:
 Frog     9 NSSSPVAATPASMSNTPDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHS 73

  Fly    80 KLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQR 144
            |||||||||||||||:::||.|:..|:.:||||:.|::.||.||..||.|::|..:|::|.||.|
 Frog    74 KLEKADILEMTVKHLRNLQRVQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTDVRTR 138

  Fly   145 LSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSAP-AIQ 208
            |..||..|.|   ||.:| |:...      |.....|||.|.:......|...:...|.|| |.:
 Frog   139 LLGHLANCMN---QINAM-NYPTQ------PQIPAAAAPHPAYGQPLVQLQGAAPQSSPAPIACK 193

  Fly   209 M-----------GGLQLIPSRLPSGEFALIM-----PNTGSAAP-----------PP--GPFAWP 244
            |           ||.||:|:  |.|:||.::     |:.||..|           ||  .|...|
 Frog   194 MGGPPVEAAKVYGGFQLVPA--PDGQFAFLITNPAFPHNGSVIPVYTNSNVGTALPPSVSPSVMP 256

  Fly   245 GSAA 248
            ...|
 Frog   257 SVTA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	bHLH-O_hairy_like	39..105	CDD:381483	46/65 (71%)
		ORANGE	114..158	CDD:128787	19/43 (44%)
hes1	NP_001011194.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		14/35 (40%)
		bHLH-O_HES1_4	33..95	CDD:381465	45/61 (74%)
		Hairy_orange	109..148	CDD:462193	18/38 (47%)
		WRPW motif. /evidence=ECO:0000255	264..267