DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpn and E(spl)mbeta-HLH

DIOPT Version :9

Sequence 1:NP_476923.1 Gene:dpn / 35800 FlyBaseID:FBgn0010109 Length:435 Species:Drosophila melanogaster
Sequence 2:NP_524505.2 Gene:E(spl)mbeta-HLH / 43152 FlyBaseID:FBgn0002733 Length:195 Species:Drosophila melanogaster


Alignment Length:235 Identity:64/235 - (27%)
Similarity:111/235 - (47%) Gaps:75/235 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 LSKA-ELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQ 98
            :||. :.||..||::|::||||||.||:|||.:::|.:.::....|:||||||||:||:|::.::
  Fly     7 MSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLR 71

  Fly    99 RQ-QLNMAI-------QSDP--SVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCA 153
            .| ||.::.       .:||  |:.:.|:.|:|..|.||::.::.:.|:...:..:|.:||....
  Fly    72 AQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRL 136

  Fly   154 NSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSAPAIQMGGLQLIPSR 218
            |.|:.:                           .||||                 :|    :|.:
  Fly   137 NYLQVV---------------------------VPSLP-----------------IG----VPLQ 153

  Fly   219 LPSGEFALIMP--------NTGSAAPPP-------GPFAW 243
            .|..:.|::.|        .:|:.:|.|       ||. |
  Fly   154 APVEDQAMVTPPPSECDSLESGACSPAPSEASSTSGPM-W 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpnNP_476923.1 HLH 39..101 CDD:238036 30/62 (48%)
ORANGE 114..158 CDD:128787 12/43 (28%)
E(spl)mbeta-HLHNP_524505.2 HLH 13..75 CDD:238036 30/61 (49%)
ORANGE 97..141 CDD:128787 12/43 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45438341
Domainoid 1 1.000 45 1.000 Domainoid score I4621
eggNOG 1 0.900 - - E1_KOG4304
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10985
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3263
SonicParanoid 00.000 Not matched by this tool.
76.870

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