Protein Alignment dpn and HELT

DIOPT Version :9

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001287710.1
• Gene: HELT / 391723
• HGNCID: 33783
• Length: 242
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 77/305 - (25%)
• Similarity: 117/305 - (38%)
• Gaps: 111/305 - (36%)

  Fly    39 ELRKT--NKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQ--- 98
            |.::|  :..::|||||.|||.|||||...:..|:.|..:  .|||||:||||||::|:::.
Human     7 ERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLRALHSAD 69

  Fly    99 ----RQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQI 159
                |::..:..:    ....|..|:.||.:.:..|::.::.::|  :....|.:.....|..::
Human    70 FPRGREKAELLAE----FANYFHYGYHECMKNLVHYLTTVERMET--KDTKYARILAFLQSKARL 128

  Fly   160 GSMSNFSNGYRGGLFPATAVTAAPTPLFP---SLPQ-DLNNNSRTESSAPAIQMGGLQLIPSRLP 220
            |:                      .|.||   |||: |.:                .||.|:
Human   129 GA----------------------EPAFPPLGSLPEPDFS----------------YQLHPA--- 152

  Fly   221 SGEFALIMPNTGSAAPPP-----GPFAWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAF 280
            ..|||...|  |.||..|     |||.||..||      .|.||..:.
Human   153 GPEFAGHSP--GEAAVFPQGSGAGPFPWPPGAA------RSPALPYLP----------------- 192

  Fly   281 SKPVNTSVPANLPENLIHTLPGQTQLPVKNSTSPPLSPISSISSH 325
            |.||..:.||                   ...||.|:|:..:..|
Human   193 SAPVPLASPA-------------------QQHSPFLTPVQGLDRH 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	HLH	39..101	CDD:238036	30/70 (43%)
		ORANGE	114..158	CDD:128787	8/43 (19%)
HELT	NP_001287710.1	bHLH-O_HELT	14..69	CDD:381414	27/56 (48%)
		Hairy_orange	87..127	CDD:400076	8/41 (20%)
		PRK14951	<133..>207	CDD:237865	32/136 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810