Protein Alignment dpn and HES5

DIOPT Version :9

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: XP_005244808.1
• Gene: HES5 / 388585
• HGNCID: 19764
• Length: 198
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 63/258 - (24%)
• Similarity: 92/258 - (35%)
• Gaps: 113/258 - (43%)

  Fly    35 LSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARH---TKLEKADILEMTVKHLQS 96
            ||..|..:..||::||.||.|||..:.:|| |:||   ::.|||   :||||||||||.|.:|:.
Human    11 LSPKEKNRLRKPVVEKMRRDRINSSIEQLK-LLLE---QEFARHQPNSKLEKADILEMAVSYLKH 71

  Fly    97 VQRQQLNM---------------AIQSDP--------------SVVQKFKTGFVECAEEVNRYVS 132
            .:.::...               |.:|.|              |:.|.:..|:..|.:|..::::
Human    72 SKGERARAPRAPSSHRAPAPPRPAARSPPPRLPAAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLT 136

  Fly   133 QMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNN 197
            .....||  :.:|..|..:                           ..|||
Human   137 LHAASDT--QMKLLYHFQR---------------------------PPAAP-------------- 158

  Fly   198 SRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPGSAAGVAAGTASAALA 260
                 :|||.:                    |....|||||         |..|..||:||.|
Human   159 -----AAPAKE--------------------PKAPGAAPPP---------ALSAKATAAAAAA 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	HLH	39..101	CDD:238036	30/64 (47%)
		ORANGE	114..158	CDD:128787	8/43 (19%)
HES5	XP_005244808.1	HLH	14..71	CDD:238036	30/60 (50%)
		Hairy_orange	118..153	CDD:295407	8/36 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840