DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpn and Hes6

DIOPT Version :9

Sequence 1:	NP_476923.1	Gene:	dpn / 35800	FlyBaseID:	FBgn0010109	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001013197.1	Gene:	Hes6 / 316626	RGDID:	1312047	Length:	234	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	63/216 - (29%)
Similarity:	96/216 - (44%)	Gaps:	31/216 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GSNGRMSNP------NGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLE 82
            |...|:..|      .||| :...:..||::||:||||||..|.||:.|:.....:     .|||
  Rat    14 GQGLRVDGPAGGCTGQGLS-SRFPQARKPLVEKKRRARINESLQELRLLLAGTEVQ-----AKLE 72

  Fly    83 KADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSA 147
            .|::||:||:.:|...|.:.....|......::|..|:::|..||:.:||....||..|...|..
  Rat    73 NAEVLELTVRRVQGALRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLN 137

  Fly   148 HL-------------NQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSR 199
            ||             :...:||..:...|..|:...|| .|.:.:::.|.| ...|..||.....
  Rat   138 HLLESMPLREGSSFRDLLGDSLAGLPGGSGRSSWPPGG-SPESPLSSPPGP-GDDLCSDLEEIPE 200

  Fly   200 TE-SSAPAIQMGGLQLIPSRL 219
            .| :..||   .|..|:|:.|
  Rat   201 AELNRVPA---EGPDLVPTSL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	HLH	39..101	CDD:238036	24/61 (39%)
dpn	NP_476923.1	ORANGE	114..158	CDD:128787	15/56 (27%)
Hes6	NP_001013197.1	HLH	37..85	CDD:238036	22/52 (42%)
Hes6	NP_001013197.1	Hairy_orange	106..144	CDD:284859	13/37 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810