Protein Alignment dpn and her1

DIOPT Version :10

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_571153.1
• Gene: her1 / 30287
• ZFINID: ZDB-GENE-980526-125
• Length: 328
• Species: Danio rerio
• Alignment Length: 454
• Identity: 103/454 - (22%)
• Similarity: 166/454 - (36%)
• Gaps: 173/454 - (38%)

  Fly    29 MSNPNGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKH 93
            |..|...|:...::..||::||:||.|||..|.||::|:|:.......::.|||||:|||:.|::
Zfish     1 MVTPKMASRRPTKRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQNPKLEKAEILELAVEY 65

  Fly    94 LQS------------------------VQRQQLNMAIQSDPSVVQK--------FKTGFVECAEE 126
            :::                        .:|.|:..|  |.|..:|.        :|.||.||
Zfish    66 IRTKTATARDQGDSSKDTHDPKPPPLLSRRPQMPCA--SIPESIQTHNSPSNPIYKAGFKEC--- 125

  Fly   127 VNRYVSQMDGIDTGVR----QRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPT--P 185
            ::|..|.:|.::...|    |.|..||:..:::|                  |...|::.||  |
Zfish   126 ISRSASFIDCVEPSQRDSFVQGLCHHLDSYSSAL------------------PHGRVSSNPTHHP 172

  Fly   186 LFPSLPQDLNNNSRTES-----SAPAIQMGGLQLIPSRL----PSGEFALIMPNTGSAAPPPGPF 241
            ..|:  .:|:..:..:|     :.|........|.|...    |:|:...:.| ..|.:|||.|
Zfish   173 WIPN--PELSCRTDVQSIGHMRANPEPYSYANSLYPKSFMHLHPTGQHPYLSP-PYSISPPPSP- 233

  Fly   242 AWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPANLPENLIHTLPGQTQL 306
                       |.:|::....::||:|                  |||...|
Zfish   234 -----------GFSSSSPPFSSSPTYL------------------SVPCQFP------------- 256

  Fly   307 PVKNSTSPPLSPISSISSHCEESRAASPTVDVMSKHSFAGVFSTPPPTSAETSFNTSGSLNLSAG 371
                  .||     |||.|..:|.::|                    |.:..|.:|: ||.:..|
Zfish   257 ------FPP-----SISPHSTDSSSSS--------------------TLSTVSLSTT-SLPVVPG 289

  Fly   372 SHDSSGCSRPLAHLQQQQVSSTSGIAKRDREAEAESSDCSLDEPSSKKFLAGAIEKSSSAWRPW 435
            .|              .||||.:    |.|.:.:..|       |..:.|..|:..:...||||
Zfish   290 PH--------------LQVSSPT----RVRFSGSVQS-------SQPRTLRRALFHNQPLWRPW 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	bHLH-O_hairy_like	39..105	CDD:381483	25/89 (28%)
		ORANGE	114..158	CDD:128787	15/55 (27%)
her1	NP_571153.1	bHLH_SF	13..73	CDD:469605	23/59 (39%)
		Hairy_orange	118..157	CDD:462193	13/41 (32%)