Protein Alignment dpn and Hes1

DIOPT Version :10

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_077336.3
• Gene: Hes1 / 29577
• RGDID: 62081
• Length: 281
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 104/253 - (41%)
• Similarity: 143/253 - (56%)
• Gaps: 47/253 - (18%)

  Fly    38 AELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQL 102
            :|.||::|||||||||||||..|::||:|||:|:|||.:||:|||||||||||||||:::||.|:
  Rat    32 SEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQM 96

  Fly   103 NMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSN 167
            ..|:.:||||:.|::.||.||..||.|::|..:|::|.||.||..||   ||.:.||.:|:
  Rat    97 TAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAMT---- 154

  Fly   168 GYRGGLFPATAVTAAPTPLFPSLPQDL------------NNNSRTESSAP----------AIQMG 210
             |.|...||......|.|..|..||..            ...:....|||          |...|
  Rat   155 -YPGQAHPALQAPPPPPPSGPGGPQHAPFAPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFG 218

  Fly   211 GLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPG-------SAAGVAAGTASAALAS 261
            |.|::|:  |.|:||.::||        |.||..|       |.:|.:.|..:.:.:|
  Rat   219 GFQVVPA--PDGQFAFLIPN--------GAFAHSGPVIPVYTSNSGTSVGPNAVSPSS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	bHLH-O_hairy_like	39..105	CDD:381483	46/65 (71%)
		ORANGE	114..158	CDD:128787	19/43 (44%)
Hes1	NP_077336.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		7/11 (64%)
		bHLH-O_HES1_4	33..95	CDD:381465	45/61 (74%)
		Hairy_orange	109..148	CDD:462193	19/41 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..206		10/47 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..281		2/12 (17%)
		WRPW motif	276..279