Protein Alignment dpn and lin-22

DIOPT Version :9

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_500281.1
• Gene: lin-22 / 177082
• WormBaseID: WBGene00003008
• Length: 173
• Species: Caenorhabditis elegans
• Alignment Length: 194
• Identity: 51/194 - (26%)
• Similarity: 91/194 - (46%)
• Gaps: 32/194 - (16%)

  Fly    13 FDCSNGYSDSYGSNGRMSNPNGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPAR 77
            |.||:...:|.|         |:|:.:..| |||:|||:||||||..|::||.::::...|:..:
 Worm     4 FLCSDTEIESDG---------GISRCKKIK-NKPLMEKKRRARINKSLSQLKQILIQDEHKNSIQ 58

  Fly    78 HTKLEKADILEMTVKHLQSVQRQQ------LNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDG 136
            |:|.||||||||.|::||.::..|      ...:|.:.|:.           .||:......::.
 Worm    59 HSKWEKADILEMAVEYLQQLRSAQPCSLSPSTSSISTPPTP-----------KEEIRNIKVPLNP 112

  Fly   137 IDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRT 200
            |.:.:...:..::     :.:|:..:|.::..:...........|..|...|.|.:.|....|:
 Worm   113 IASFLNPMMQQYV-----AYQQLAQLSMYTQLFNNPAGVPLRADAGVTAQSPELAEKLKIEDRS 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	HLH	39..101	CDD:238036	30/61 (49%)
		ORANGE	114..158	CDD:128787	3/43 (7%)
lin-22	NP_500281.1	bHLH_O_HES	29..82	CDD:381416	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I6616
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4933
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	1	1.000	-	-		oto19460
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3263
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790