Protein Alignment dpn and helt

DIOPT Version :10

• Sequence 1: NP_476923.1
• Gene: dpn / 35800
• FlyBaseID: FBgn0010109
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: XP_017951230.1
• Gene: helt / 100486939
• XenbaseID: XB-GENE-984868
• Length: 252
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 73/313 - (23%)
• Similarity: 117/313 - (37%)
• Gaps: 100/313 - (31%)

  Fly    47 IMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSD-- 109
            ::|||||.|||.||:||...:..|:.|.  ...|||||:||||||::|:::....|......|
 Frog    33 VIEKRRRDRINRCLSELGKTVPMALAKQ--NSGKLEKAEILEMTVQYLRALHATDLPRGRDKDLL 95

  Fly   110 PSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLF 174
            ......|..|:.||.:.:..|::.:        :|:....|:.|..:..:.|.::.|.
 Frog    96 SEFANYFHYGYHECMKNLVHYLTTV--------ERMETKDNKYARIVAFLQSKAHLST------- 145

  Fly   175 PATAVTAAPTPLFPSLPQ---DLNNNSRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAP 236
                     .|:|..|.:   ....:|..:.::|         :.|..|        |.:|
 Frog   146 ---------EPIFSPLQEVEVSCQLHSPPDYASP---------VDSTFP--------PCSG---- 180

  Fly   237 PPGPFAWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPANLPENLIHTLP 301
              |.|:|.|:|       .|..|..:.:||.::                           :...|
 Frog   181 --GSFSWHGTA-------RSPTLNYLGSPTAMS---------------------------LSCSP 209

  Fly   302 GQTQLPVKNSTSPPLSPISSISSHCEESRAASPTVDVMSKHSFAGVFSTPPPT 354
            .|     :::.|..|||:.|:..|.......|.|       |..||.||..||
 Frog   210 SQ-----QSAHSTFLSPVQSLDRHYLNFLGHSHT-------SNFGVHSTQHPT 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpn	NP_476923.1	bHLH-O_hairy_like	39..105	CDD:381483	27/57 (47%)
		ORANGE	114..158	CDD:128787	8/43 (19%)
helt	XP_017951230.1	bHLH-O_HELT	30..85	CDD:381414	26/53 (49%)
		Hairy_orange	101..141	CDD:462193	9/47 (19%)