| Sequence 1: | NP_001260800.2 | Gene: | LRP1 / 35799 | FlyBaseID: | FBgn0053087 | Length: | 4752 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005166314.1 | Gene: | lrp8 / 557734 | ZFINID: | ZDB-GENE-050506-134 | Length: | 1008 | Species: | Danio rerio |
| Alignment Length: | 876 | Identity: | 306/876 - (34%) |
|---|---|---|---|
| Similarity: | 419/876 - (47%) | Gaps: | 154/876 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2613 GVLAPDGRRCIAPVNTSCGLSQYNCHSGECIPLELTCDNVTHCADGSDEFRSYCIFRQCPETHFM 2677
Fly 2678 CQNHRCIPKEHKCDGEQQCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRCGSGECIPRKF 2742
Fly 2743 LCDSLKDCRDFSDEKMCAPIPCEKNDMTFVHCGNSTI-CIMPRWRCDGDPDCPDGTDELDCANHT 2806
Fly 2807 SLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINC----RTECRHNQFAC-DKTCIPASWQC 2866
Fly 2867 DGKSDCEDGSDEGPQCPNRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLGDEGSEDEGPQCGG 2931
Fly 2932 VAHIPDCPPPAHLCTSGLCIDSHYVCDGDEDCPGGDDEYEGCVPAFQPHSCPGGSLMHQCQDGLC 2996
Fly 2997 IFKNQTCDGKPDCGDGSDETSSLCAH-TRGCNGTDDFRCKNGACIHADLLCDRRNDCADFSDEEL 3060
Fly 3061 --CNVNECLIPD-ICEHECEDKVVGYQCHCRPGYKVLPKSPHLCTDIDECDEQQPCSQTCINTYG 3122
Fly 3123 SYKCLCAKGYALVD-HHTCKATSNVSMELIFSNRYYIRQVDMTGNG-SILINELSNAVALDYDWD 3185
Fly 3186 SQCLYWSDVTSTVGTIKRYCPKENKTQ---TLHQAMLKNPDGLAVDWVAKNLYWCDKGLDTIEVS 3247
Fly 3248 QLDGKYRKVLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAGMDGSNPKMIIRDGLGWPNAL 3312
Fly 3313 TISFETQQLFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIAVWEGHIYWSDWETKS 3377
Fly 3378 IEYCSIFNGQNCTTLITTIHRPMDLRVFHPYRQQQPMSGNPCLAAN-----CSTLCVLSPE---- 3433
Fly 3434 EPYYKCMCPTNFILADDGRTC---RANCTAA 3461 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRP1 | NP_001260800.2 | LDLa | 87..118 | CDD:197566 | |
| LDLa | 126..163 | CDD:238060 | |||
| EGF_CA | 246..283 | CDD:214542 | |||
| Ldl_recept_b | 449..487 | CDD:278487 | |||
| LY | 472..513 | CDD:214531 | |||
| LY | 817..852 | CDD:214531 | |||
| LDLa | 1057..1092 | CDD:197566 | |||
| LDLa | 1104..1134 | CDD:238060 | |||
| FXa_inhibition | 1289..1317 | CDD:291342 | |||
| LY | 1434..1476 | CDD:214531 | |||
| LY | 1477..1521 | CDD:214531 | |||
| LY | 1533..1567 | CDD:214531 | |||
| LY | 1568..1611 | CDD:214531 | |||
| FXa_inhibition | 1639..1676 | CDD:291342 | |||
| LY | 1794..1838 | CDD:214531 | |||
| LY | 2078..2112 | CDD:214531 | |||
| NHL | <2082..>2152 | CDD:302697 | |||
| NHL repeat | 2082..2120 | CDD:271320 | |||
| FXa_inhibition | 2269..2303 | CDD:291342 | |||
| LY | 2430..2471 | CDD:214531 | |||
| LY | 2475..2517 | CDD:214531 | |||
| LDLa | 2630..2661 | CDD:238060 | 12/30 (40%) | ||
| LDLa | 2671..2702 | CDD:238060 | 15/30 (50%) | ||
| LDLa | 2727..2759 | CDD:238060 | 4/31 (13%) | ||
| LDLa | 2773..2802 | CDD:238060 | 15/29 (52%) | ||
| LDLa | 2810..2844 | CDD:238060 | 14/33 (42%) | ||
| LDLa | 2848..2878 | CDD:238060 | 15/30 (50%) | ||
| LDLa | 2887..2916 | CDD:197566 | 7/28 (25%) | ||
| LDLa | 2938..2969 | CDD:197566 | 12/30 (40%) | ||
| LDLa | 2989..3015 | CDD:197566 | 11/25 (44%) | ||
| LDLa | 3030..3061 | CDD:238060 | 14/32 (44%) | ||
| EGF_CA | 3062..>3091 | CDD:214542 | 11/29 (38%) | ||
| EGF_CA | 3103..3141 | CDD:214542 | 19/38 (50%) | ||
| LY | 3212..3254 | CDD:214531 | 22/44 (50%) | ||
| LY | 3255..3297 | CDD:214531 | 23/41 (56%) | ||
| LY | 3299..3340 | CDD:214531 | 11/40 (28%) | ||
| LY | 3354..3389 | CDD:214531 | 11/34 (32%) | ||
| LDLa | 3458..3490 | CDD:238060 | 3/4 (75%) | ||
| LDLa | 3499..3533 | CDD:238060 | |||
| LDLa | 3582..3616 | CDD:238060 | |||
| LDLa | 3621..3652 | CDD:197566 | |||
| LDLa | 3663..3697 | CDD:238060 | |||
| LDLa | 3702..3736 | CDD:238060 | |||
| LDLa | 3776..3808 | CDD:197566 | |||
| LDLa | 3818..3849 | CDD:197566 | |||
| LDLa | 3860..3894 | CDD:238060 | |||
| NHL | 4029..>4158 | CDD:302697 | |||
| NHL repeat | 4034..4074 | CDD:271320 | |||
| NHL repeat | 4076..4115 | CDD:271320 | |||
| LY | 4108..4150 | CDD:214531 | |||
| NHL repeat | 4121..4158 | CDD:271320 | |||
| EGF_CA | <4386..4414 | CDD:238011 | |||
| EGF_CA | 4415..4450 | CDD:238011 | |||
| lrp8 | XP_005166314.1 | LDLa | 66..98 | CDD:197566 | 15/31 (48%) |
| Ldl_recept_a | 107..144 | CDD:278486 | 19/91 (21%) | ||
| Ldl_recept_a | 191..224 | CDD:278486 | 15/32 (47%) | ||
| Ldl_recept_a | 240..274 | CDD:278486 | 14/33 (42%) | ||
| Ldl_recept_a | 278..313 | CDD:278486 | 14/43 (33%) | ||
| LDLa | 322..352 | CDD:197566 | 13/29 (45%) | ||
| FXa_inhibition | 362..396 | CDD:291342 | 14/35 (40%) | ||
| EGF_CA | 398..428 | CDD:214542 | 17/29 (59%) | ||
| LY | 463..504 | CDD:214531 | 13/41 (32%) | ||
| LY | 511..552 | CDD:214531 | 22/40 (55%) | ||
| Ldl_recept_b | 573..613 | CDD:278487 | 14/39 (36%) | ||
| LY | 597..639 | CDD:214531 | 11/41 (27%) | ||
| Ldl_recept_b | 660..699 | CDD:278487 | 9/38 (24%) | ||
| FXa_inhibition | 718..755 | CDD:291342 | 12/36 (33%) | ||
| IgaA | 913..>985 | CDD:284503 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||