| Sequence 1: | NP_001260800.2 | Gene: | LRP1 / 35799 | FlyBaseID: | FBgn0053087 | Length: | 4752 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005155618.1 | Gene: | vldlr / 393897 | ZFINID: | ZDB-GENE-040426-803 | Length: | 877 | Species: | Danio rerio |
| Alignment Length: | 828 | Identity: | 294/828 - (35%) |
|---|---|---|---|
| Similarity: | 438/828 - (52%) | Gaps: | 139/828 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2670 QCPETHFMCQNHRCIPKEHKCDGEQQCGDGSDETPLLCKCQSEDIDMHPSNNNTKEMPDMFRCGS 2734
Fly 2735 GECIPRKFLCDSLKDCRDFSDE--KMCAPIPCEKNDMTFVHCG-NSTICIMPRWRCDGDPDCPDG 2796
Fly 2797 TDELDCANHTSLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINCR-TECRHNQFAC-DKTC 2859
Fly 2860 IPASWQCDGKSDCEDGSDEGPQ-CPNRP-----CRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLG 2918
Fly 2919 DEGSEDEGPQCGGVAHIPDCPPPAHLCTSGLCIDSHYVCDGDEDCPGGDDEYEGCVPAFQPHSCP 2983
Fly 2984 GGSLMHQCQDGLCIFKNQTCDGKPDCGDGSDETSSLCAHTRGCNGTDDFRCKNGACIHADLLCDR 3048
Fly 3049 RNDCADFSDEEL--CNVNECLIPD-ICEHECEDKVVGYQCHCRPGYKVLPKSPHLCTDIDECDEQ 3110
Fly 3111 QPCSQTCINTYGSYKCLCAKGYALVDHHT--CKATSNVSME--LIFSNRYYIRQVDMTGNG-SIL 3170
Fly 3171 INELSNAVALDYDWDSQCLYWSD-----VTSTVGTIKRYCPKENKTQTLHQAMLKN---PDGLAV 3227
Fly 3228 DWVAKNLYWCDKGLDTIEVSQLDGKYRKVLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAG 3292
Fly 3293 MDGSNPKMIIRDGLGWPNALTISFETQQLFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHH 3357
Fly 3358 IFAIAVWEGHIYWSDWETKSIEYCSIFNGQNCTTLITTIHRPMDLRVFHPYRQQQPMSG-NPCLA 3421
Fly 3422 ----ANCSTLCVLSPE----EPYYKCMCPTNFILADDGRTCRANCTAA 3461 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRP1 | NP_001260800.2 | LDLa | 87..118 | CDD:197566 | |
| LDLa | 126..163 | CDD:238060 | |||
| EGF_CA | 246..283 | CDD:214542 | |||
| Ldl_recept_b | 449..487 | CDD:278487 | |||
| LY | 472..513 | CDD:214531 | |||
| LY | 817..852 | CDD:214531 | |||
| LDLa | 1057..1092 | CDD:197566 | |||
| LDLa | 1104..1134 | CDD:238060 | |||
| FXa_inhibition | 1289..1317 | CDD:291342 | |||
| LY | 1434..1476 | CDD:214531 | |||
| LY | 1477..1521 | CDD:214531 | |||
| LY | 1533..1567 | CDD:214531 | |||
| LY | 1568..1611 | CDD:214531 | |||
| FXa_inhibition | 1639..1676 | CDD:291342 | |||
| LY | 1794..1838 | CDD:214531 | |||
| LY | 2078..2112 | CDD:214531 | |||
| NHL | <2082..>2152 | CDD:302697 | |||
| NHL repeat | 2082..2120 | CDD:271320 | |||
| FXa_inhibition | 2269..2303 | CDD:291342 | |||
| LY | 2430..2471 | CDD:214531 | |||
| LY | 2475..2517 | CDD:214531 | |||
| LDLa | 2630..2661 | CDD:238060 | |||
| LDLa | 2671..2702 | CDD:238060 | 15/30 (50%) | ||
| LDLa | 2727..2759 | CDD:238060 | 15/33 (45%) | ||
| LDLa | 2773..2802 | CDD:238060 | 15/29 (52%) | ||
| LDLa | 2810..2844 | CDD:238060 | 17/33 (52%) | ||
| LDLa | 2848..2878 | CDD:238060 | 14/30 (47%) | ||
| LDLa | 2887..2916 | CDD:197566 | 15/28 (54%) | ||
| LDLa | 2938..2969 | CDD:197566 | 4/30 (13%) | ||
| LDLa | 2989..3015 | CDD:197566 | 10/25 (40%) | ||
| LDLa | 3030..3061 | CDD:238060 | 13/32 (41%) | ||
| EGF_CA | 3062..>3091 | CDD:214542 | 14/29 (48%) | ||
| EGF_CA | 3103..3141 | CDD:214542 | 18/39 (46%) | ||
| LY | 3212..3254 | CDD:214531 | 16/44 (36%) | ||
| LY | 3255..3297 | CDD:214531 | 20/41 (49%) | ||
| LY | 3299..3340 | CDD:214531 | 10/40 (25%) | ||
| LY | 3354..3389 | CDD:214531 | 12/34 (35%) | ||
| LDLa | 3458..3490 | CDD:238060 | 2/4 (50%) | ||
| LDLa | 3499..3533 | CDD:238060 | |||
| LDLa | 3582..3616 | CDD:238060 | |||
| LDLa | 3621..3652 | CDD:197566 | |||
| LDLa | 3663..3697 | CDD:238060 | |||
| LDLa | 3702..3736 | CDD:238060 | |||
| LDLa | 3776..3808 | CDD:197566 | |||
| LDLa | 3818..3849 | CDD:197566 | |||
| LDLa | 3860..3894 | CDD:238060 | |||
| NHL | 4029..>4158 | CDD:302697 | |||
| NHL repeat | 4034..4074 | CDD:271320 | |||
| NHL repeat | 4076..4115 | CDD:271320 | |||
| LY | 4108..4150 | CDD:214531 | |||
| NHL repeat | 4121..4158 | CDD:271320 | |||
| EGF_CA | <4386..4414 | CDD:238011 | |||
| EGF_CA | 4415..4450 | CDD:238011 | |||
| vldlr | XP_005155618.1 | LDLa | 29..63 | CDD:238060 | 18/33 (55%) |
| LDLa | 67..99 | CDD:197566 | 15/46 (33%) | ||
| Ldl_recept_a | 107..145 | CDD:278486 | 17/40 (43%) | ||
| Ldl_recept_a | 149..184 | CDD:278486 | 17/34 (50%) | ||
| Ldl_recept_a | 234..269 | CDD:278486 | 17/58 (29%) | ||
| Ldl_recept_a | 272..308 | CDD:278486 | 15/71 (21%) | ||
| LDLa | 316..346 | CDD:238060 | 11/29 (38%) | ||
| FXa_inhibition | 356..390 | CDD:291342 | 12/35 (34%) | ||
| EGF_CA | 392..426 | CDD:214542 | 17/34 (50%) | ||
| NHL | 479..>570 | CDD:302697 | 33/99 (33%) | ||
| LY | 504..541 | CDD:214531 | 14/36 (39%) | ||
| NHL repeat | 511..551 | CDD:271320 | 19/39 (49%) | ||
| Ldl_recept_b | 564..604 | CDD:278487 | 14/39 (36%) | ||
| LY | 588..630 | CDD:214531 | 10/41 (24%) | ||
| Ldl_recept_b | 651..690 | CDD:278487 | 10/38 (26%) | ||
| FXa_inhibition | 707..745 | CDD:291342 | 13/37 (35%) | ||
| Mucin | <723..817 | CDD:250634 | 14/30 (47%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||