| Sequence 1: | NP_001260800.2 | Gene: | LRP1 / 35799 | FlyBaseID: | FBgn0053087 | Length: | 4752 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_017212215.1 | Gene: | ldlrb / 393460 | ZFINID: | ZDB-GENE-040426-1254 | Length: | 906 | Species: | Danio rerio |
| Alignment Length: | 802 | Identity: | 274/802 - (34%) |
|---|---|---|---|
| Similarity: | 385/802 - (48%) | Gaps: | 123/802 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2733 GSGECIPRKFLCDSLKDCRDFSDEKMCAPIPCE-----------KNDMTFVHCGNSTICIMPRWR 2786
Fly 2787 CDGDPDCPD------------GTDELDCANHT-----------------SLSCDPGQFRCAS--G 2820
Fly 2821 NCIAGSWHCDGEKDCPDGSDEINC-RTECRHNQFACDK-TCIPASWQCDGKSDCEDGSDEGPQCP 2883
Fly 2884 --NRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPSGLGDEGSEDEGPQCGGVAHIPDCPPPAHLCT 2946
Fly 2947 SGLCIDSHYVCDGDEDCPGGDDEYEGCVPAFQPHSCPGGSLMHQCQDGLCIFKNQTCDGKPDCGD 3011
Fly 3012 GSDETSSLCAHTRGCNGTDDFRCKNGACIHADLLCDRRNDCADFSDEEL--CNVNECLIPD-ICE 3073
Fly 3074 HECEDKVVGYQCHCRPGYKVLPKSPHLCTDIDECDEQQPCSQTCINTYGSYKCLCAKGYALVDHH 3138
Fly 3139 T--CKATSNVSMELIFSNRYYIRQVDMTGNGS----ILINELSNAVALDYDWDSQCLYWSDVT-- 3195
Fly 3196 ---STVGTIKRYCPKENKTQ--TLHQAMLKNPDGLAVDWVAKNLYWCDKGLDTIEVSQLDGKYRK 3255
Fly 3256 VLINEYLREPRGIALHPYQQHIFWSDWGDSPHIGKAGMDGSNPKMIIRDGLGWPNALTISFETQQ 3320
Fly 3321 LFWGDAREDTISVSDLDGNHTRLLLARSINPLLNLHHIFAIAVWEGHIYWSDWETKSIEYCSIFN 3385
Fly 3386 GQNCTTLITTIHRPMDLRVFHPYRQQQPMSGNPC-----LAANCSTLCVLSP----EEPYYKCMC 3441
Fly 3442 PTNFILADDGRTC--RANCTAA 3461 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRP1 | NP_001260800.2 | LDLa | 87..118 | CDD:197566 | |
| LDLa | 126..163 | CDD:238060 | |||
| EGF_CA | 246..283 | CDD:214542 | |||
| Ldl_recept_b | 449..487 | CDD:278487 | |||
| LY | 472..513 | CDD:214531 | |||
| LY | 817..852 | CDD:214531 | |||
| LDLa | 1057..1092 | CDD:197566 | |||
| LDLa | 1104..1134 | CDD:238060 | |||
| FXa_inhibition | 1289..1317 | CDD:291342 | |||
| LY | 1434..1476 | CDD:214531 | |||
| LY | 1477..1521 | CDD:214531 | |||
| LY | 1533..1567 | CDD:214531 | |||
| LY | 1568..1611 | CDD:214531 | |||
| FXa_inhibition | 1639..1676 | CDD:291342 | |||
| LY | 1794..1838 | CDD:214531 | |||
| LY | 2078..2112 | CDD:214531 | |||
| NHL | <2082..>2152 | CDD:302697 | |||
| NHL repeat | 2082..2120 | CDD:271320 | |||
| FXa_inhibition | 2269..2303 | CDD:291342 | |||
| LY | 2430..2471 | CDD:214531 | |||
| LY | 2475..2517 | CDD:214531 | |||
| LDLa | 2630..2661 | CDD:238060 | |||
| LDLa | 2671..2702 | CDD:238060 | |||
| LDLa | 2727..2759 | CDD:238060 | 7/25 (28%) | ||
| LDLa | 2773..2802 | CDD:238060 | 6/40 (15%) | ||
| LDLa | 2810..2844 | CDD:238060 | 15/35 (43%) | ||
| LDLa | 2848..2878 | CDD:238060 | 14/30 (47%) | ||
| LDLa | 2887..2916 | CDD:197566 | 15/28 (54%) | ||
| LDLa | 2938..2969 | CDD:197566 | 11/30 (37%) | ||
| LDLa | 2989..3015 | CDD:197566 | 13/25 (52%) | ||
| LDLa | 3030..3061 | CDD:238060 | 14/32 (44%) | ||
| EGF_CA | 3062..>3091 | CDD:214542 | 13/29 (45%) | ||
| EGF_CA | 3103..3141 | CDD:214542 | 22/39 (56%) | ||
| LY | 3212..3254 | CDD:214531 | 17/43 (40%) | ||
| LY | 3255..3297 | CDD:214531 | 19/41 (46%) | ||
| LY | 3299..3340 | CDD:214531 | 11/40 (28%) | ||
| LY | 3354..3389 | CDD:214531 | 10/34 (29%) | ||
| LDLa | 3458..3490 | CDD:238060 | 3/4 (75%) | ||
| LDLa | 3499..3533 | CDD:238060 | |||
| LDLa | 3582..3616 | CDD:238060 | |||
| LDLa | 3621..3652 | CDD:197566 | |||
| LDLa | 3663..3697 | CDD:238060 | |||
| LDLa | 3702..3736 | CDD:238060 | |||
| LDLa | 3776..3808 | CDD:197566 | |||
| LDLa | 3818..3849 | CDD:197566 | |||
| LDLa | 3860..3894 | CDD:238060 | |||
| NHL | 4029..>4158 | CDD:302697 | |||
| NHL repeat | 4034..4074 | CDD:271320 | |||
| NHL repeat | 4076..4115 | CDD:271320 | |||
| LY | 4108..4150 | CDD:214531 | |||
| NHL repeat | 4121..4158 | CDD:271320 | |||
| EGF_CA | <4386..4414 | CDD:238011 | |||
| EGF_CA | 4415..4450 | CDD:238011 | |||
| ldlrb | XP_017212215.1 | None | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||