| Sequence 1: | NP_001260800.2 | Gene: | LRP1 / 35799 | FlyBaseID: | FBgn0053087 | Length: | 4752 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011238756.1 | Gene: | Lrp8 / 16975 | MGIID: | 1340044 | Length: | 1010 | Species: | Mus musculus |
| Alignment Length: | 774 | Identity: | 281/774 - (36%) |
|---|---|---|---|
| Similarity: | 402/774 - (51%) | Gaps: | 83/774 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2728 DMFRCGSGECIPRKFLCDSLKDCRDFSDEKMCAPIPCEKNDMTFVHCGNSTICIMPRWRCDGDPD 2792
Fly 2793 CPDGTDE--LDCANH----TSLSCDPGQFRCASGNCIAGSWHCDGEKDCPDGSDEINCRTECRHN 2851
Fly 2852 QFAC-DKTCIPASWQCDGKSDCEDGSDEGPQCPNRPCRPHLFQCKSSGRCIPQKWVCDGEKDCPS 2915
Fly 2916 GLGDEGSEDEGPQCG----GVAHIP-DCPPPAHL-CTSGLCIDSHYVCDGDEDCPGGDDEYEGCV 2974
Fly 2975 PAFQPHSCPGGSLMHQCQDGLCIFKNQTCDGKPDCGDGSDETSSLCAHTRGCNGTDDFRCKNGAC 3039
Fly 3040 IHADLLCDRRNDCADFSDE--ELC-------------NVNECLIPD-ICEHECEDKVVGYQCHCR 3088
Fly 3089 PGYKVLPKSPHLCTDIDECDEQQPCSQTCINTYGSYKCLCAKGYALVDHHT--CKATSNVSMELI 3151
Fly 3152 FSNRYYIRQVDMTGNG-SILINELSNAVALDYDWDSQCLYWSDVTSTVGTIKRYCPKENKTQ--- 3212
Fly 3213 ---TLHQAMLKNPDGLAVDWVAKNLYWCDKGLDTIEVSQLDGKYRKVLINEYLREPRGIALHPYQ 3274
Fly 3275 QHIFWSDWGDSPHIGKAGMDGSNPKMIIRDGLGWPNALTISFETQQLFWGDAREDTISVSDLDGN 3339
Fly 3340 HTRLLLARSINPLLNLHHIFAIAVWEGHIYWSDWETKSIEYCSIFNGQNCTTLITTIHRPMDLRV 3404
Fly 3405 FHPYRQQQPMSGNPC-LAA----NCSTLCVLSPE----EPYYKCMCPTNFILADDGRTC 3454 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LRP1 | NP_001260800.2 | LDLa | 87..118 | CDD:197566 | |
| LDLa | 126..163 | CDD:238060 | |||
| EGF_CA | 246..283 | CDD:214542 | |||
| Ldl_recept_b | 449..487 | CDD:278487 | |||
| LY | 472..513 | CDD:214531 | |||
| LY | 817..852 | CDD:214531 | |||
| LDLa | 1057..1092 | CDD:197566 | |||
| LDLa | 1104..1134 | CDD:238060 | |||
| FXa_inhibition | 1289..1317 | CDD:291342 | |||
| LY | 1434..1476 | CDD:214531 | |||
| LY | 1477..1521 | CDD:214531 | |||
| LY | 1533..1567 | CDD:214531 | |||
| LY | 1568..1611 | CDD:214531 | |||
| FXa_inhibition | 1639..1676 | CDD:291342 | |||
| LY | 1794..1838 | CDD:214531 | |||
| LY | 2078..2112 | CDD:214531 | |||
| NHL | <2082..>2152 | CDD:302697 | |||
| NHL repeat | 2082..2120 | CDD:271320 | |||
| FXa_inhibition | 2269..2303 | CDD:291342 | |||
| LY | 2430..2471 | CDD:214531 | |||
| LY | 2475..2517 | CDD:214531 | |||
| LDLa | 2630..2661 | CDD:238060 | |||
| LDLa | 2671..2702 | CDD:238060 | |||
| LDLa | 2727..2759 | CDD:238060 | 15/30 (50%) | ||
| LDLa | 2773..2802 | CDD:238060 | 15/30 (50%) | ||
| LDLa | 2810..2844 | CDD:238060 | 16/33 (48%) | ||
| LDLa | 2848..2878 | CDD:238060 | 12/30 (40%) | ||
| LDLa | 2887..2916 | CDD:197566 | 14/28 (50%) | ||
| LDLa | 2938..2969 | CDD:197566 | 14/31 (45%) | ||
| LDLa | 2989..3015 | CDD:197566 | 11/25 (44%) | ||
| LDLa | 3030..3061 | CDD:238060 | 13/32 (41%) | ||
| EGF_CA | 3062..>3091 | CDD:214542 | 11/29 (38%) | ||
| EGF_CA | 3103..3141 | CDD:214542 | 18/39 (46%) | ||
| LY | 3212..3254 | CDD:214531 | 20/47 (43%) | ||
| LY | 3255..3297 | CDD:214531 | 18/41 (44%) | ||
| LY | 3299..3340 | CDD:214531 | 12/40 (30%) | ||
| LY | 3354..3389 | CDD:214531 | 12/34 (35%) | ||
| LDLa | 3458..3490 | CDD:238060 | |||
| LDLa | 3499..3533 | CDD:238060 | |||
| LDLa | 3582..3616 | CDD:238060 | |||
| LDLa | 3621..3652 | CDD:197566 | |||
| LDLa | 3663..3697 | CDD:238060 | |||
| LDLa | 3702..3736 | CDD:238060 | |||
| LDLa | 3776..3808 | CDD:197566 | |||
| LDLa | 3818..3849 | CDD:197566 | |||
| LDLa | 3860..3894 | CDD:238060 | |||
| NHL | 4029..>4158 | CDD:302697 | |||
| NHL repeat | 4034..4074 | CDD:271320 | |||
| NHL repeat | 4076..4115 | CDD:271320 | |||
| LY | 4108..4150 | CDD:214531 | |||
| NHL repeat | 4121..4158 | CDD:271320 | |||
| EGF_CA | <4386..4414 | CDD:238011 | |||
| EGF_CA | 4415..4450 | CDD:238011 | |||
| Lrp8 | XP_011238756.1 | LDLa | 41..75 | CDD:238060 | 15/30 (50%) |
| LDLa | 79..111 | CDD:197566 | 16/35 (46%) | ||
| LDLa | 121..157 | CDD:238060 | 18/40 (45%) | ||
| LDLa | 200..232 | CDD:197566 | 15/36 (42%) | ||
| LDLa | 256..286 | CDD:238060 | 13/29 (45%) | ||
| LDLa | 292..326 | CDD:238060 | 13/35 (37%) | ||
| LDLa | 330..366 | CDD:381805 | 15/35 (43%) | ||
| FXa_inhibition | 387..421 | CDD:373209 | 11/35 (31%) | ||
| EGF_CA | 423..453 | CDD:214542 | 15/29 (52%) | ||
| LY | 492..527 | CDD:214531 | 13/38 (34%) | ||
| LY | 537..578 | CDD:214531 | 20/40 (50%) | ||
| Ldl_recept_b | 599..639 | CDD:278487 | 15/39 (38%) | ||
| LY | 623..665 | CDD:214531 | 12/41 (29%) | ||
| Ldl_recept_b | 686..725 | CDD:278487 | 9/38 (24%) | ||
| FXa_inhibition | 744..781 | CDD:373209 | 11/36 (31%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||