DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mlh1 and PMS2

DIOPT Version :10

Sequence 1:NP_477022.1 Gene:Mlh1 / 35796 FlyBaseID:FBgn0011659 Length:664 Species:Drosophila melanogaster
Sequence 2:NP_001393795.1 Gene:PMS2 / 5395 HGNCID:9122 Length:924 Species:Homo sapiens


Alignment Length:17 Identity:8/17 - (47%)
Similarity:11/17 - (64%) Gaps:1/17 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LLTHEGALLAFSGF-GD 39
            ||:|.|..:|..|: ||
Human   304 LLSHRGERVAARGYWGD 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mlh1NP_477022.1 mutl 8..317 CDD:273155 8/17 (47%)
Mlh1_C 426..664 CDD:465109
PMS2NP_001393795.1 mutl 75..406 CDD:273155 8/17 (47%)
mutL 76..915 CDD:234630 8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

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