DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gasz and ITN1

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_187842.1	Gene:	ITN1 / 820414	AraportID:	AT3G12360	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	250	Identity:	64/250 - (25%)
Similarity:	108/250 - (43%)	Gaps:	29/250 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EQKLYDAVVAGDLKTMQEEMRKLVLQ-VDQPVKGGLNLLMLACREGHYKIVEWLLERAGANVNRQ 104
            |..|:.|...|.|..::|.::....: :.:..:.|.:.|.:|..:||:.|||.||:. .|.:::.
plant   130 ETALFTAADKGHLDVVKELLKYSSRESIAKKNRSGYDPLHIAAIQGHHAIVEVLLDH-DATLSQT 193

  Fly   105 L--DSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINVSEKYGMTPFMFACQNGFAGVVR-LLI 166
            .  .:..||:.|....|     .|.:..||.:.|.::.:|..........|.:.|...|:: ||.
plant   194 FGPSNATPLVSAAMRGH-----TEVVNQLLSKAGNLLEISRSNNKNALHLAARQGHVEVIKALLS 253

  Fly   167 KDASF-DAVDNQGCTAIFHAIEKNHVEVVKLLVEAGANATIANNKG-YTPTQVAECHGYYDLLEI 229
            ||... ..:|.:|.||:..|::....||||||::|.....:..:|. .|...||......:::|:
plant   254 KDPQLARRIDKKGQTALHMAVKGQSSEVVKLLLDADPAIVMQPDKSCNTALHVATRKKRAEIVEL 318

  Fly   230 LPRPASTYLVPTHFLGYNTL-RDHIPRIFLKSDCP-----EYFQEL---NGILEA 275
            |.....|        ..||| |||...:.:....|     .|.:|.   :|.|.|
plant   319 LLSLPDT--------NANTLTRDHKTALDIAEGLPLSEESSYIKECLARSGALRA 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	24/99 (24%)
		ANK repeat	73..106	CDD:293786	11/34 (32%)
		ANK	74..198	CDD:238125	37/127 (29%)
		ANK repeat	110..143	CDD:293786	8/32 (25%)
		Ank_2	111..208	CDD:289560	27/98 (28%)
		ANK repeat	145..175	CDD:293786	7/31 (23%)
		ANK repeat	177..208	CDD:293786	11/30 (37%)
		SAM	273..324	CDD:197735	1/2 (50%)
		SAM_superfamily	273..321	CDD:188886	1/2 (50%)
		PHA03233	<289..>366	CDD:223016
ITN1	NP_187842.1	ANK repeat	73..126	CDD:293786
		ANK repeat	129..161	CDD:293786	6/30 (20%)
		Ank_2	133..>321	CDD:393464	50/193 (26%)
		ANK repeat	163..195	CDD:293786	11/32 (34%)
		ANK repeat	235..263	CDD:293786	7/27 (26%)
		ANK repeat	265..297	CDD:293786	11/31 (35%)
		PGG	413..519	CDD:372845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000