DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gasz and espnlb

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	XP_017207109.1	Gene:	espnlb / 566645	ZFINID:	ZDB-GENE-070912-481	Length:	1005	Species:	Danio rerio

Alignment Length:	452	Identity:	100/452 - (22%)
Similarity:	170/452 - (37%)	Gaps:	100/452 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SKPAPYVDPEQKLYDAVVAGDLKTMQEEMRKLVLQVDQPVKGGLNLLMLACREGHYKIVEWLLER 96
            ::|..|         |..:|||.:::..|......||.....|...|.|||:|||..:||:|::.
Zfish   138 ARPVHY---------AAASGDLTSLKMLMSSSPRCVDCQTGTGATPLYLACQEGHLHVVEYLVKD 193

  Fly    97 AGANVNRQL-DSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINVSEKYGMTPFMFACQNGFAG 160
            .||||:.|. |.:..|..|.:..|     ...:|.|.......::..:|.|.|...||...|...
Zfish   194 CGANVHVQAKDGMSVLHAAAHMGH-----YALVVWLASFTDLDLSCQDKNGATALHFAASEGHHR 253

  Fly   161 VV-RLLIKDASFDAVDNQGCTAIFHAIEKNHVEVVKLLVEAGANATIANNKGYTPTQVAECHGYY 224
            :| |||:..... ..|:.|.|.:..|.|...:|..::|:....:....::.|:|...:||.:||:
Zfish   254 IVERLLLMGVKV-LKDHWGGTPLHDAAENGELECCRVLLNNHISPLERDSDGFTALHLAEYNGYH 317

  Fly   225 DLLEILPRPASTYLVPTHFL------------GYNTLRD--HIPRIFL-------------KSDC 262
            |....| |.|.....|...|            .|..:.|  |..::.:             ...|
Zfish   318 DCANFL-RDAGAQQSPDIVLIEEERTLFSTADPYQDIEDLKHKSKMEICKPVNEVSPQPRPSPAC 381

  Fly   263 PEYFQELNGILEAINIG-NMVQYFAIARISLADFLV---MDEQ----------SLREIGIEYPIF 313
            .|....|....:|...| ..:|:..:|...:..|.:   ::|:          |:|:.||.
Zfish   382 LETSSTLLDSSQAKKAGAGTIQHMQVASTVVTSFNMRKHLEEEEAMLSHKSMRSMRQAGIT---- 442

  Fly   314 RHKILTGILDFHLHHWSNSSIARVKKDEMNNFYEILLITASHLQHLVIIQASLRFI-LKNQEHNK 377
              .:.||             ...|:|.|            :.:..||.::|:|..| .....|::
Zfish   443 --AVFTG-------------QTNVQKGE------------NDIGPLVTLEANLADIDSLIPTHDE 480

  Fly   378 MGQP-----SEMQVAAMKSNLQGYRDVLNQITKTVKYL----GSFSPSQNPLFIDFNEILAE 430
            .|:|     .::.|..:::.||...|...:...:.|::    ..:|...|.:...|.|:|.|
Zfish   481 NGRPIAEWKRQVMVRKLQARLQDEDDHSKKQEISGKHIEVDGWRYSQVHNVILGPFGELLTE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	29/97 (30%)
		ANK repeat	73..106	CDD:293786	16/33 (48%)
		ANK	74..198	CDD:238125	38/125 (30%)
		ANK repeat	110..143	CDD:293786	5/32 (16%)
		Ank_2	111..208	CDD:289560	22/97 (23%)
		ANK repeat	145..175	CDD:293786	9/30 (30%)
		ANK repeat	177..208	CDD:293786	6/30 (20%)
		SAM	273..324	CDD:197735	12/64 (19%)
		SAM_superfamily	273..321	CDD:188886	11/61 (18%)
		PHA03233	<289..>366	CDD:223016	14/89 (16%)
espnlb	XP_017207109.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000