DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gasz and ankrd67

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_001122202.1	Gene:	ankrd67 / 566073	ZFINID:	ZDB-GENE-050419-160	Length:	422	Species:	Danio rerio

Alignment Length:	178	Identity:	50/178 - (28%)
Similarity:	86/178 - (48%)	Gaps:	13/178 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 EMRKLVLQVDQPVKG----GLNLLMLACREGHYKIVEWLLERAGANVNRQLDSLMPLMMACNTTH 119
            ::.:|:|.....|:|    |::.|.||...|:...|..||:| ||:.|.:..:....|..|
Zfish   198 DVAELLLDNGADVEGGKGVGMSPLQLAVLVGNEAGVRLLLQR-GADANMRGPNGRTAMHLC---- 257

  Fly   120 KDPCLAE-RIVGLLLRHGAVINVSEKYGMTPFMFACQNGFAGVVRLLI-KDASFDAVDNQGCTAI 182
              .|..: :|:..||..||.::|.:....:|...|.::|...||.||| ..|..:..||...|.:
Zfish   258 --ACSGDKKILQQLLAGGARVDVRDGDVASPLHLAARSGSRAVVHLLILNGAGLEDRDNLKMTPL 320

  Fly   183 FHAIEKNHVEVVKLLVEAGANATIANNKGYTPTQVAECHGYYDLLEIL 230
            .::..::::|..|||:..||:.......|.||..:|...|:..:|::|
Zfish   321 HYSTLRDNIEAAKLLLHYGADVNAVERLGQTPLHLASERGHCKVLKVL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	24/86 (28%)
		ANK repeat	73..106	CDD:293786	13/36 (36%)
		ANK	74..198	CDD:238125	36/125 (29%)
		ANK repeat	110..143	CDD:293786	9/33 (27%)
		Ank_2	111..208	CDD:289560	27/98 (28%)
		ANK repeat	145..175	CDD:293786	9/30 (30%)
		ANK repeat	177..208	CDD:293786	7/30 (23%)
		SAM	273..324	CDD:197735
		SAM_superfamily	273..321	CDD:188886
		PHA03233	<289..>366	CDD:223016
ankrd67	NP_001122202.1	Ank_4	55..104	CDD:290365
		ANK repeat	55..81	CDD:293786
		ANK	78..204	CDD:238125	1/5 (20%)
		ANK repeat	83..115	CDD:293786
		Ank_2	89..181	CDD:289560
		ANK repeat	119..148	CDD:293786
		ANK repeat	150..181	CDD:293786
		Ank_2	155..246	CDD:289560	16/48 (33%)
		ANK repeat	183..211	CDD:293786	2/12 (17%)
		ANK repeat	216..246	CDD:293786	12/30 (40%)
		ANK	217..245	CDD:197603	11/28 (39%)
		ANK	244..369	CDD:238125	35/131 (27%)
		ANK repeat	249..280	CDD:293786	9/36 (25%)
		Ank_4	250..303	CDD:290365	15/58 (26%)
		ANK repeat	285..313	CDD:293786	9/27 (33%)
		Ank_2	287..378	CDD:289560	24/82 (29%)
		ANK repeat	315..346	CDD:293786	7/30 (23%)
		ANK	343..>404	CDD:238125	7/26 (27%)
		ANK repeat	348..378	CDD:293786	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578738
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930