DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gasz and Iqank1

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_001357849.1	Gene:	Iqank1 / 432964	MGIID:	3588184	Length:	572	Species:	Mus musculus

Alignment Length:	214	Identity:	48/214 - (22%)
Similarity:	81/214 - (37%)	Gaps:	52/214 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 YVDPEQKL----YDAVV--------------AGDLKTMQEEMRKLVLQVDQPVKGGLNLLMLACR 83
            |:|..:||    |.|:|              ..:.:..:||:::....::...:|.|..:....:
Mouse    92 YLDEMEKLQKEAYLALVRQEQEAARRQREKEEAEERARREELQRRRRLLEAAFEGDLGEIRQVLK 156

  Fly    84 EGHYKIVEWLLERAGANVNRQLDSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINVSEKYGMT 148
            |     ||.|:.|.|..                  :.:...|.|    |.|..|.:...:.:|.|
Mouse   157 E-----VEQLMTREGVG------------------YDEDGKARR----LQRRVATVECEDSHGNT 194

  Fly   149 PFMFACQNGFAGVVRLLIKDASFDAVDNQ----GCTAIFHAIEKNHVEVVKLLVEAGANATIANN 209
            |...|...|....::||   |...|..|.    |.|.::.|....|:|.|:.|::.||:..:..:
Mouse   195 PLSEAAAGGQTMAIQLL---AELGANPNTKGAFGRTPLYRAAFGGHLEAVEELLKIGADPRMYAD 256

  Fly   210 KGYTPTQVAECHGYYDLLE 228
            .|.||.|||.......:|:
Mouse   257 DGSTPEQVASLAAVASVLQ 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	19/114 (17%)
		ANK repeat	73..106	CDD:293786	8/32 (25%)
		ANK	74..198	CDD:238125	28/127 (22%)
		ANK repeat	110..143	CDD:293786	5/32 (16%)
		Ank_2	111..208	CDD:289560	24/100 (24%)
		ANK repeat	145..175	CDD:293786	9/29 (31%)
		ANK repeat	177..208	CDD:293786	9/34 (26%)
		SAM	273..324	CDD:197735
		SAM_superfamily	273..321	CDD:188886
		PHA03233	<289..>366	CDD:223016
Iqank1	NP_001357849.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62
		ANK repeat	191..222	CDD:293786	10/33 (30%)
		ANK 1. /evidence=ECO:0000255	191..220		9/31 (29%)
		ANKYR	<192..314	CDD:223738	26/87 (30%)
		Ank_4	192..245	CDD:372654	16/55 (29%)
		ANK repeat	224..255	CDD:293786	9/30 (30%)
		ANK 2. /evidence=ECO:0000255	224..253		9/28 (32%)
		Borrelia_P83	<287..>400	CDD:114011
		AAA_9	427..>479	CDD:372311
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100