DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gasz and nompC

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_523483.2	Gene:	nompC / 33768	FlyBaseID:	FBgn0016920	Length:	1761	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	101/501 - (20%)
Similarity:	162/501 - (32%)	Gaps:	195/501 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EQKLYDAVVAGD---LKTMQEEMRKLVLQ--VDQPVKGGLNLLMLACREGHYKIVEWLLERAGAN 100
            |...:...|||:   |..|...|....:|  :::....|...|::||..||.::|..||    ||
  Fly   622 ETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIACHRGHMELVNNLL----AN 682

  Fly   101 VNR----QLDSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINVSEKYGMTPFMFACQNGFAGV 161
            ..|    ..:....|.:|....:...|.|      ||.:.|.||...:.|.|....|..|||..:
  Fly   683 HARVDVFDTEGRSALHLAAERGYLHVCDA------LLTNKAFINSKSRVGRTALHLAAMNGFTHL 741

  Fly   162 VRLLIKD-----------------------------------ASFDAVDNQG------------- 178
            |:.||||                                   |:.||.|:.|
  Fly   742 VKFLIKDHNAVIDILTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYS 806

  Fly   179 ---------------------------------------------------------CTAIFHAI 186
                                                                     .|.:..|.
  Fly   807 EVAKLFLQQHPSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVISARNKLTDATPLQLAA 871

  Fly   187 EKNHVEVVKLLVEAGANATIANNKGYTPTQVAECHGYYDLLEILPRPASTY-------LVPTHFL 244
            |..|.:|||.||.|||:.|..|..|:|...:|..:|:..:|::|....|..       |.|.|..
  Fly   872 EGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLRINSKKLGLTPLHVA 936

  Fly   245 GY----NTLRDHIPRI--FLKSDCPEYFQELNGILEAINIGNMVQYFAIARISLADFLVMDEQSL 303
            .|    :|:|:.:..:  .:||:.|. .|.|.|
  Fly   937 AYYGQADTVRELLTSVPATVKSETPT-GQSLFG-------------------------------- 968

  Fly   304 REIGIEYPIFRHKILTGILDFHLHHWS----------NSSIARVKKDEMNNFYEILLIT--ASHL 356
             ::|.|         :|:...||..:|          ||:..:|....:.|.|..|.:.  ..|:
  Fly   969 -DLGTE---------SGMTPLHLAAFSGNENVVRLLLNSAGVQVDAATIENGYNPLHLACFGGHM 1023

  Fly   357 QHLVIIQASLRFILKNQEHNKMGQPSEMQVAAMKSNLQGYRDVLNQ 402
            ..:.::.:....:|::|:.|  |: :.:.:|||..::|....:|.|
  Fly  1024 SVVGLLLSRSAELLQSQDRN--GR-TGLHIAAMHGHIQMVEILLGQ 1066

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	27/105 (26%)
		ANK repeat	73..106	CDD:293786	12/36 (33%)
		ANK	74..198	CDD:238125	44/232 (19%)
		ANK repeat	110..143	CDD:293786	9/32 (28%)
		Ank_2	111..208	CDD:289560	38/201 (19%)
		ANK repeat	145..175	CDD:293786	14/64 (22%)
		ANK repeat	177..208	CDD:293786	14/100 (14%)
		SAM	273..324	CDD:197735	3/50 (6%)
		SAM_superfamily	273..321	CDD:188886	2/47 (4%)
		PHA03233	<289..>366	CDD:223016	13/88 (15%)
nompC	NP_523483.2	ANK repeat	129..157	CDD:293786
		Ank_2	131..228	CDD:289560
		ANK	155..319	CDD:238125
		ANK repeat	159..186	CDD:293786
		ANK repeat	232..265	CDD:293786
		Ank_2	237..331	CDD:289560
		ANK	263..387	CDD:238125
		ANK repeat	267..298	CDD:293786
		ANK repeat	300..331	CDD:293786
		Ank_2	305..398	CDD:289560
		ANK	329..454	CDD:238125
		ANK repeat	367..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		Ank_2	405..498	CDD:289560
		ANK	428..555	CDD:238125
		ANK repeat	433..463	CDD:293786
		ANK repeat	469..499	CDD:293786
		ANK	496..641	CDD:238125	5/18 (28%)
		ANK repeat	501..532	CDD:293786
		Ank_2	507..616	CDD:289560
		ANK repeat	534..575	CDD:293786
		ANK repeat	577..616	CDD:293786
		Ank_2	625..722	CDD:289560	28/106 (26%)
		ANK	654..780	CDD:238125	32/135 (24%)
		ANK repeat	660..690	CDD:293786	12/33 (36%)
		ANK repeat	692..723	CDD:293786	9/36 (25%)
		Ank_2	697..790	CDD:289560	23/98 (23%)
		ANK	720..847	CDD:238125	17/126 (13%)
		ANK repeat	725..757	CDD:293786	11/31 (35%)
		ANK repeat	759..790	CDD:293786	3/30 (10%)
		Ank_5	779..834	CDD:290568	5/54 (9%)
		ANK	787..915	CDD:238125	23/127 (18%)
		ANK repeat	792..824	CDD:293786	1/31 (3%)
		ANK repeat	861..893	CDD:293786	13/31 (42%)
		Ank_4	865..915	CDD:290365	19/49 (39%)
		Ank_4	929..995	CDD:290365	18/108 (17%)
		ANK repeat	932..972	CDD:293786	11/73 (15%)
		ANK	969..1096	CDD:238125	23/110 (21%)
		ANK repeat	974..1007	CDD:293786	7/32 (22%)
		Ank_2	979..1074	CDD:289560	20/91 (22%)
		ANK repeat	1009..1041	CDD:293786	5/31 (16%)
		ANK	1039..1159	CDD:238125	9/31 (29%)
		ANK repeat	1043..1074	CDD:293786	8/27 (30%)
		Ank_2	1048..1135	CDD:289560	6/19 (32%)
		ANK repeat	1076..1101	CDD:293786
		ANK repeat	1109..1134	CDD:293786
		Ion_trans	<1393..1598	CDD:278921
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
	2	1.910