DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gasz and TANC2

DIOPT Version :9

Sequence 1:NP_610362.1 Gene:Gasz / 35795 FlyBaseID:FBgn0033273 Length:461 Species:Drosophila melanogaster
Sequence 2:XP_011522899.1 Gene:TANC2 / 26115 HGNCID:30212 Length:2075 Species:Homo sapiens


Alignment Length:300 Identity:83/300 - (27%)
Similarity:120/300 - (40%) Gaps:84/300 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MMSNLCKYGPPPDSDSDSSYD--GF-----YFSDKVKRSKPAPYVDPEQK-----LYDAVVAGDL 53
            |::.|.::|...|:.|:|...  |:     |.|..|...|....||...|     |..|.:.|.|
Human   974 MVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHL 1038

  Fly    54 KTMQEEMRKLVLQVDQPVKG---GL--------NLLMLACREGHYKIVEWLL----------ERA 97
                 |:.|.::|.|..:.|   |:        ..|:.|...|:.:||.:||          |||
Human  1039 -----EVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERA 1098

  Fly    98 GANVNRQLDSL------------------------------------MPLMMACNTTHKDPCLAE 126
            ..|   ..|||                                    :||.......|      .
Human  1099 QIN---SFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGH------W 1154

  Fly   127 RIVGLLLRHGAVINVSEKYGMTPFMFACQNGFAGVVR-LLIKDASFDAVDNQGCTAIFHAIEKNH 190
            :||.|||.|||.:|:::|.|.||.|.|...|..|.|. ||.:.||...:|.:|.||:..|..|.|
Human  1155 QIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGH 1219

  Fly   191 VEVVKLLVEAGANATIANNKGYTPTQVAECHGYYDLLEIL 230
            :.||:.||:.||....|:..|.||..:|..:|..::::.|
Human  1220 LSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GaszNP_610362.1 Ank_2 44..141 CDD:289560 35/153 (23%)
ANK repeat 73..106 CDD:293786 13/53 (25%)
ANK 74..198 CDD:238125 49/178 (28%)
ANK repeat 110..143 CDD:293786 12/32 (38%)
Ank_2 111..208 CDD:289560 37/97 (38%)
ANK repeat 145..175 CDD:293786 12/30 (40%)
ANK repeat 177..208 CDD:293786 12/30 (40%)
SAM 273..324 CDD:197735
SAM_superfamily 273..321 CDD:188886
PHA03233 <289..>366 CDD:223016
TANC2XP_011522899.1 AAA_16 415..>457 CDD:289934
Ank_4 962..1011 CDD:290365 10/36 (28%)
ANK repeat 963..989 CDD:293786 4/14 (29%)
ANK 986..1194 CDD:238125 56/221 (25%)
ANK repeat 991..1022 CDD:293786 8/30 (27%)
Ank_2 996..1132 CDD:289560 32/143 (22%)
ANK repeat 1108..1138 CDD:293786 0/29 (0%)
Ank_2 1112..1204 CDD:289560 25/97 (26%)
ANK repeat 1140..1171 CDD:293786 12/36 (33%)
ANK 1168..1293 CDD:238125 33/91 (36%)
ANK repeat 1174..1204 CDD:293786 12/29 (41%)
Ank_2 1178..1270 CDD:289560 28/81 (35%)
ANK repeat 1206..1237 CDD:293786 12/30 (40%)
ANK repeat 1239..1270 CDD:293786 5/20 (25%)
ANK repeat 1272..1302 CDD:293786
TPR_11 1331..1406 CDD:290150
TPR repeat 1331..1356 CDD:276809
TPR repeat 1361..1404 CDD:276809
TPR_11 1377..1441 CDD:290150
TPR repeat 1409..1438 CDD:276809
TFIIA 1487..>1714 CDD:281188
ANAPC1 <1512..1583 CDD:289618
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.