DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gasz and AgaP_AGAP009937

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	XP_319063.4	Gene:	AgaP_AGAP009937 / 1279352	VectorBaseID:	AGAP009937	Length:	1520	Species:	Anopheles gambiae

Alignment Length:	403	Identity:	98/403 - (24%)
Similarity:	162/403 - (40%)	Gaps:	75/403 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 AVVAGDLKTMQEEMRK-LVLQVDQPVKGGLNLLMLACREGHYKIVEWLLER-------------- 96
            |..||||:.:.|.:.. .|..::.....|||.|.||.::|||.||..||:|
Mosquito    10 AARAGDLQKLIEYLETGQVTDINTCNTNGLNALHLAAKDGHYDIVNELLKRGALVDNATKKGNTA 74

  Fly    97 --------------------AGANVNRQLDSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINV 141
                                |..||..| :...||.||....| |.|     |..||..||...:
Mosquito    75 LHIASLAGQKEIIQLLLQYNASVNVQSQ-NGFTPLYMAAQENH-DEC-----VNYLLAKGANPAL 132

  Fly   142 SEKYGMTPFMFACQNGFAGVVRLLIKDASFDAVDNQG---CTAIFHAIEKNHVEVVKLLVEAGAN 203
            :.:.|.||...|.|.|...||.:|::.      |.:|   ..|:..|.:|:.|:..|||:|...|
Mosquito   133 ATEDGFTPLAVAMQQGHDKVVAVLLES------DTRGKVRLPALHIAAKKDDVKAAKLLLENEHN 191

  Fly   204 ATIANNKGYTPTQVAECHGYYDLLEIL-PRPASTYLVPTHFLGYNTLRDHIPRIFLKSDCPEYFQ 267
            ..:::..|:||..:|..:|..::.::| .:.|.......|    |....|:...:.|.:..:...
Mosquito   192 PDVSSKSGFTPLHIAAHYGNVNVAQLLIEKGADVNFTAKH----NITPLHVACKWGKLNMVKLLI 252

  Fly   268 ELNGILEAINIGNMVQYFAIARISLADFLVMDEQSLREIGIEYPIFRHKILTGILDFHL----HH 328
            ..:|.:::|....:......|| |..|.::   :.|.|.|.|   ...|...|:...|:    .|
Mosquito   253 ANHGRIDSITRDGLTPLHCAAR-SGHDQVI---EVLLEHGAE---IISKTKNGLAPLHMAAQGEH 310

  Fly   329 WSNSSIARVKK---DEMNNFYEILLITASHLQHLVIIQASLRFILKNQEHN--KMGQPSEMQVAA 388
            .|.:.|..:.|   |::...|...|..|:|..|:.:.:..|.   :|.:.|  .:...:.:.:|.
Mosquito   311 VSAARILLMNKSPVDDITIDYLTALHVAAHCGHVKVAKLLLD---RNADPNARALNGFTPLHIAC 372

  Fly   389 MKSNLQGYRDVLN 401
            .|:.::....:||
Mosquito   373 KKNRIKVVELLLN 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	37/128 (29%)
		ANK repeat	73..106	CDD:293786	18/66 (27%)
		ANK	74..198	CDD:238125	47/160 (29%)
		ANK repeat	110..143	CDD:293786	12/32 (38%)
		Ank_2	111..208	CDD:289560	31/99 (31%)
		ANK repeat	145..175	CDD:293786	9/29 (31%)
		ANK repeat	177..208	CDD:293786	10/33 (30%)
		SAM	273..324	CDD:197735	11/50 (22%)
		SAM_superfamily	273..321	CDD:188886	10/47 (21%)
		PHA03233	<289..>366	CDD:223016	20/83 (24%)
AgaP_AGAP009937	XP_319063.4	Ank_4	3..58	CDD:290365	18/47 (38%)
		ANK repeat	4..35	CDD:293786	7/24 (29%)
		ANK	32..157	CDD:238125	38/131 (29%)
		ANK repeat	37..68	CDD:293786	14/30 (47%)
		Ank_2	42..130	CDD:289560	27/94 (29%)
		ANK repeat	70..101	CDD:293786	3/30 (10%)
		ANK repeat	103..128	CDD:293786	10/30 (33%)
		Ank_2	108..228	CDD:289560	38/131 (29%)
		ANK repeat	169..196	CDD:293786	9/26 (35%)
		ANK	193..318	CDD:238125	27/135 (20%)
		ANK repeat	198..229	CDD:293786	7/30 (23%)
		Ank_2	203..294	CDD:289560	18/101 (18%)
		ANK repeat	231..262	CDD:293786	5/34 (15%)
		ANK	259..384	CDD:238125	27/134 (20%)
		ANK repeat	264..289	CDD:293786	6/28 (21%)
		ANK repeat	297..361	CDD:293786	15/66 (23%)
		Ank_4	298..351	CDD:290365	12/52 (23%)
		Ank_2	335..425	CDD:289560	11/54 (20%)
		ANK	358..483	CDD:238125	5/28 (18%)
		ANK repeat	363..394	CDD:293786	4/23 (17%)
		ANK repeat	396..427	CDD:293786
		ANK repeat	429..460	CDD:293786
		Ank_4	432..483	CDD:290365
		ANK	457..582	CDD:238125
		ANK repeat	462..493	CDD:293786
		Ank_2	467..558	CDD:289560
		ANK repeat	495..526	CDD:293786
		ANK	524..648	CDD:238125
		ANK repeat	528..558	CDD:293786
		Ank_2	533..624	CDD:289560
		ANK repeat	561..586	CDD:293786
		ANK repeat	594..625	CDD:293786
		ANK	622..747	CDD:238125
		ANK repeat	627..656	CDD:293786
		Ank_2	632..723	CDD:289560
		ANK repeat	660..691	CDD:293786
		ANK repeat	693..723	CDD:293786
		Ank_5	713..767	CDD:290568
		ANK repeat	726..756	CDD:293786
		ZU5	897..1001	CDD:128514
		Death_ank	1410..1493	CDD:260029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910