DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gasz and REL2

DIOPT Version :9

Sequence 1:NP_610362.1 Gene:Gasz / 35795 FlyBaseID:FBgn0033273 Length:461 Species:Drosophila melanogaster
Sequence 2:XP_308995.3 Gene:REL2 / 1270310 VectorBaseID:AGAP006747 Length:1132 Species:Anopheles gambiae


Alignment Length:249 Identity:57/249 - (22%)
Similarity:92/249 - (36%) Gaps:85/249 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 DAVVAGDLKTMQEEMRKLVLQVDQPVKGG--------------------LNLLMLACREG----- 85
            |.|.:||.....|.:|||:..:  .:..|                    ||.|..|.|..     
Mosquito   698 DLVASGDDSRQGEMLRKLLALI--KLFAGDVNRSRQLLASHWTAANQQQLNCLHAAIRRNDTTIA 760

  Fly    86 --------HYKIVEWLLERAGANVNRQLDSLMPLMMACNTTHKDPCLAERIVGLLLRHGAVINVS 142
                    .|::.|.||:..    |.:.::.:.|.::||        :|.||..||..||.::..
Mosquito   761 CKLIELLHEYQLAEELLDLP----NDRNETGLHLAVSCN--------SEPIVKALLGAGAKLHYC 813

  Fly   143 EKYGMTPFMFACQNGFAGVVRLLIKDAS--FDAVDNQGCTAIFHAIEKNHVEVVKLLVEAGANAT 205
            :..|.||...|.......:||||:....  .|..::.|.||:..|:...::::.::|:||||:..
Mosquito   814 DYRGNTPLHRAVVENVPDMVRLLLLQGGLRLDCTNDDGLTALQAAVYARNLKITRILLEAGASVR 878

  Fly   206 ------------IA------------------------NNKGYTPTQVAECHGY 223
                        ||                        ||.||||.|:|:...:
Mosquito   879 EKDLKHGNNILHIAVDNDALDIVHYILEEVKEELGRERNNAGYTPLQLADAKSH 932

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GaszNP_610362.1 Ank_2 44..141 CDD:289560 29/127 (23%)
ANK repeat 73..106 CDD:293786 11/65 (17%)
ANK 74..198 CDD:238125 34/158 (22%)
ANK repeat 110..143 CDD:293786 10/32 (31%)
Ank_2 111..208 CDD:289560 30/134 (22%)
ANK repeat 145..175 CDD:293786 9/31 (29%)
ANK repeat 177..208 CDD:293786 11/66 (17%)
SAM 273..324 CDD:197735
SAM_superfamily 273..321 CDD:188886
PHA03233 <289..>366 CDD:223016
REL2XP_308995.3 RHD-n_Relish 188..389 CDD:143644
IPT_NFkappaB 396..498 CDD:238582
Ank_2 <741..814 CDD:289560 20/84 (24%)
ANK repeat 747..781 CDD:293786 7/37 (19%)
ANK 778..905 CDD:238125 31/138 (22%)
ANK repeat 783..814 CDD:293786 10/38 (26%)
Ank_2 788..881 CDD:289560 28/100 (28%)
ANK repeat 816..881 CDD:293786 18/64 (28%)
Ank_2 855..951 CDD:289560 16/78 (21%)
ANK repeat 919..951 CDD:293786 6/14 (43%)
Death_NFkB-like 1053..1124 CDD:260024
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X100
TreeFam 00.000 Not matched by this tool.
11.000

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