DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gasz and asz1

DIOPT Version :9

Sequence 1:	NP_610362.1	Gene:	Gasz / 35795	FlyBaseID:	FBgn0033273	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_001121415.1	Gene:	asz1 / 100158503	XenbaseID:	XB-GENE-986015	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	80/351 - (22%)
Similarity:	144/351 - (41%)	Gaps:	63/351 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GPPPDSDSDSSYDGFYFSDKVKRSKPAPYVDPEQKLY-DAVVAGDLKTMQEEMRKLVLQVDQPVK 72
            |....||||..:|......:.:..:..|..:..:.:: .|:..|::|.           |:|.:.
Frog    11 GGGESSDSDDGWDMGEARQQDELIENNPVNESTEDIFKKALTTGNVKI-----------VEQLLN 64

  Fly    73 GGLNL----------LMLACREGHYKIVEWLLERAGANVNRQLDSLMPLMMACNTTHKDPCLAER 127
            .|||:          ||.|....:.:::..||:| |||.:.:.|....||.||.....:..:. :
Frog    65 SGLNVECCFLFGWTPLMYAASVANLEMIRLLLDR-GANASFEKDKFSVLMAACTAQAGEEKIV-K 127

  Fly   128 IVGLLLRHGAVINVSEKYGMTPFMFACQNGFAGVVRLLI-KDASFDAVDNQGCTAIFHAIEKNHV 191
            .|.|||...|..|::.:..|||.|::.:.|...||.||: ..|..:|.|....|.:..|......
Frog   128 CVDLLLSRNADPNIACRKQMTPIMYSAREGHLQVVSLLVAHGADINAQDENDYTGLAWAAHDGRK 192

  Fly   192 EVVKLLVEAGANATIANNKGYTPTQVAECHGYYDLLEILPRPAST---------------YL--V 239
            .:|..::|.||:.|::..||.||.::|....:.::..||...|::               ||  .
Frog   193 NMVLKMLELGADKTLSTKKGETPAEIARKLNHLEIFSILSFSANSGQGKMTLNKEEAIYRYLKIQ 257

  Fly   240 PTHFL----GYNTLRDHIPRIFLKSDCPEYFQELNGILEAINIGNMVQYFAIARISLADFLVMDE 300
            |...|    .|:|..|                 |...|..:::.::.:.|....|:|...|...|
Frog   258 PDQELKYTNSYSTSSD-----------------LEVFLCGLDLEHLTELFKENDITLKQLLHFKE 305

  Fly   301 QSLREIGIEYPIFRHKILTGILDFHL 326
            :.|:::|:...:...||:..:.:..:
Frog   306 EELKKVGVCCEVDCKKIVGAVKEIQV 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasz	NP_610362.1	Ank_2	44..141	CDD:289560	27/107 (25%)
		ANK repeat	73..106	CDD:293786	12/42 (29%)
		ANK	74..198	CDD:238125	38/134 (28%)
		ANK repeat	110..143	CDD:293786	10/32 (31%)
		Ank_2	111..208	CDD:289560	29/97 (30%)
		ANK repeat	145..175	CDD:293786	11/30 (37%)
		ANK repeat	177..208	CDD:293786	7/30 (23%)
		SAM	273..324	CDD:197735	10/50 (20%)
		SAM_superfamily	273..321	CDD:188886	10/47 (21%)
		PHA03233	<289..>366	CDD:223016	8/38 (21%)
asz1	NP_001121415.1	Ank_2	<50..101	CDD:289560	15/62 (24%)
		ANK	75..199	CDD:238125	35/125 (28%)
		ANK repeat	75..107	CDD:293786	9/32 (28%)
		Ank_2	80..176	CDD:289560	31/97 (32%)
		ANK repeat	109..143	CDD:293786	10/34 (29%)
		ANK repeat	145..176	CDD:293786	11/30 (37%)
		Ank_5	165..219	CDD:290568	15/53 (28%)
		ANK repeat	178..209	CDD:293786	7/30 (23%)
		SAM_ASZ1	267..330	CDD:188920	14/79 (18%)
		SAM	267..330	CDD:197735	14/79 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47586
OrthoDB	1	1.010	-	-		D1428188at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.020