DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RagC-D and gtr2

DIOPT Version :9

Sequence 1:	NP_610361.1	Gene:	RagC-D / 35793	FlyBaseID:	FBgn0033272	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_588251.1	Gene:	gtr2 / 2539088	PomBaseID:	SPCC777.05	Length:	314	Species:	Schizosaccharomyces pombe

Alignment Length:	320	Identity:	187/320 - (58%)
Similarity:	245/320 - (76%)	Gaps:	22/320 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KPR-ILLMGMRRSGKSSIQKVVFHKMSPNETLFLESTSKIVKDDINNSSFVQFQIWDFPGQIDFF 103
            ||| |:|||:|||||||||||||:||.||||||||||||:.:|.|  |||:.|.:||||||:|.|
pombe     2 KPRKIILMGLRRSGKSSIQKVVFYKMPPNETLFLESTSKLTQDHI--SSFIDFSVWDFPGQVDVF 64

  Fly   104 EPTFDSDMIFGGCGALVFVIDAKDDYNEALTKFKNTVLQAYKVNKRIKFEVFIHKVDGISDDSKM 168
            :..||.:.||...|||:|||||:|||.:||.:...||.:...:|..|..|||||||||:||:.|:
pombe    65 DAAFDFESIFTQVGALIFVIDAQDDYLDALARLHVTVARVVTINPNICIEVFIHKVDGLSDEFKI 129

  Fly   169 ESQRDIHQRSSDDLNEAGLDQIHLSFHLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFIPNS 233
            ::||||.||:.|:|.:.||:.:.:|||||||:|||||||||:|:|||||||||||||||||..||
pombe   130 DTQRDIQQRTQDELADIGLENVPISFHLTSIFDHSIFEAFSRVIQKLIPQLPTLENLLNIFCSNS 194

  Fly   234 GIEKAFLFDVVSKIYIATDSSPVDMQTYELCCDMIDVVIDLSSIYSS-------------EETAF 285
            .:|||:||||:||||:||||||||:|:||:|.|.|||::|:.|||..             :||
pombe   195 LVEKAYLFDVLSKIYVATDSSPVDVQSYEICSDFIDVILDIGSIYGRSSQLKPGHSPEILDET-- 257

  Fly   286 DSGSSSLIKLNNNTILYLREVNKFLALVCILREENFNRQGVIDYNFICFRDAISEVFELR 345
                ||:|:|:|:.:|:|||:|::|||:||:|.:||.:.|:|:||..|.:.||..:|..|
pombe   258 ----SSVIRLSNDLVLFLREMNQYLALICIVRADNFEKSGLIEYNVQCLQTAIQSIFSPR 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RagC-D	NP_610361.1	RagC_like	42..216	CDD:206745	108/174 (62%)
gtr2	NP_588251.1	Gem1	1..>155	CDD:224025	91/154 (59%)
gtr2	NP_588251.1	RagC_like	5..177	CDD:206745	107/173 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	308	1.000	Domainoid score	I247
eggNOG	1	0.900	-	-		E1_KOG3887
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39141
Inparanoid	1	1.050	377	1.000	Inparanoid score	I428
OMA	1	1.010	-	-		QHG53655
OrthoFinder	1	1.000	-	-		FOG0002298
OrthoInspector	1	1.000	-	-		oto100606
orthoMCL	1	0.900	-	-		OOG6_102660
Panther	1	1.100	-	-	LDO	PTHR11259
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R533
SonicParanoid	1	1.000	-	-		X1521
TreeFam	1	0.960	-	-
	14	13.860