DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8708 and C1GALT1

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_064541.1	Gene:	C1GALT1 / 56913	HGNCID:	24337	Length:	363	Species:	Homo sapiens

Alignment Length:	348	Identity:	166/348 - (47%)
Similarity:	224/348 - (64%)	Gaps:	35/348 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TLIAGLVVGYCL-AQIFSSIA--------------PHESLYPYLSRRFSDSQVATGGQLAPE-QS 73
            |.:.|..:|:.| :|:||.:.              ||        .|.||.    .||...| |.
Human    11 TFLCGSAIGFLLCSQLFSILLGEKVDTQPNVLHNDPH--------ARHSDD----NGQNHLEGQM 63

  Fly    74 GLKHD---HRNDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSSGADEE 135
            ....|   |:::|..:||.|.::|||||||||.|.|.:|||:|||.||.:|||.:|||||..:::
Human    64 NFNADSSQHKDENTDIAENLYQKVRILCWVMTGPQNLEKKAKHVKATWAQRCNKVLFMSSEENKD 128

  Fly   136 LPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPETPVH 200
            .|.|.|...|||:.|:.|..:||:||:.|:..|||:|.|||||||.:::|:|::|..|:||.|::
Human   129 FPAVGLKTKEGRDQLYWKTIKAFQYVHEHYLEDADWFLKADDDTYVILDNLRWLLSKYDPEEPIY 193

  Fly   201 FGFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNVTAG 265
            ||.:|||:||||||||||||:||:|||:|| |:.....| |...:.: ||:.:|||||.:||.||
Human   194 FGRRFKPYVKQGYMSGGAGYVLSKEALKRF-VDAFKTDK-CTHSSSI-EDLALGRCMEIMNVEAG 255

  Fly   266 DSRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPNSFYVLD 330
            ||||.||:....||:||||||.....:.||||||.||...:|..||||||:|||||...:.|.|:
Human   256 DSRDTIGKETFHPFVPEHHLIKGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELE 320

  Fly   331 YLIYHLKPYGLLRSLEP-LPAKL 352
            ||:|||:|||.|...:| ||.::
Human   321 YLVYHLRPYGYLYRYQPTLPERI 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
C1GALT1	NP_064541.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	41..72		10/42 (24%)
C1GALT1	NP_064541.1	Galactosyl_T	107..>221	CDD:328824	64/113 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3122
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	348	1.000	Inparanoid score	I2298
Isobase	1	0.950	-	0	Normalized mean entropy	S3251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		otm40618
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.780