DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and si:dkey-202e17.1

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_005170092.1	Gene:	si:dkey-202e17.1 / 555344	ZFINID:	ZDB-GENE-060503-810	Length:	316	Species:	Danio rerio

Alignment Length:	327	Identity:	137/327 - (41%)
Similarity:	201/327 - (61%)	Gaps:	25/327 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FTLIAGLVVGYCLAQIFSSIAPHESLYPYLSRRFSDSQVATGGQLAPEQSGLKH---DHRNDNVS 85
            |..::|:.|     .||.:|.     |.::.:..:.|.|    ::|...|.:||   .:||..:.
Zfish     8 FLFLSGVAV-----SIFLTIT-----YSHVQKTRTSSFV----RIARNISTVKHTVAQNRNATLD 58

  Fly    86 VAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSSGADEELPTVKLDVGEGRENL 150
            .::    :||:||||||.|.|.:.:.:||..||||||:.:|:|:| .:.:.||:.|:|.|||..|
Zfish    59 SSQ----KVRVLCWVMTQPQNLQSRTQHVHATWGKRCDTILYMTS-KNTDFPTIGLNVSEGRNQL 118

  Fly   151 WAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPETPVHFGFKFKPFVKQGYMS 215
            :.|...||:|::.||.:|||:|.||||||:.||||:|:.|..::.|.|::||.:|:|||.|||||
Zfish   119 YWKTIRAFQYIHKHHLDDADWFLKADDDTFVVIENLRHSLSKHSSEDPLYFGRRFRPFVAQGYMS 183

  Fly   216 GGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNVTAGDSRDEIGRGRMFPFI 280
            |||||:||:|||||| |:|..: .:|...|.: ||:.:|:|||.:.|..|||||..||....|:.
Zfish   184 GGAGYVLSKEALRRF-VKGFAD-GLCTHTTEL-EDVGMGQCMEKMKVEMGDSRDVFGRQVFHPYP 245

  Fly   281 PEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPNSFYVLDYLIYHLKPYGLLRSL 345
            |.::|:.....:..||..|.:|...:|..||||.||||||:.....:.|:|..|||:|||.....
Zfish   246 PGNYLVRQLRRQRPWYLIYDHYTPVEGPGCCSDFAISFHYINAVEMHTLEYYTYHLRPYGYKYRF 310

  Fly   346 EP 347
            .|
Zfish   311 NP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
si:dkey-202e17.1	XP_005170092.1	Galactosyl_T	<139..>229	CDD:304462	50/92 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3636
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		mtm6507
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.780