DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and c1galt1b

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_956345.1	Gene:	c1galt1b / 337131	ZFINID:	ZDB-GENE-030131-9075	Length:	374	Species:	Danio rerio

Alignment Length:	407	Identity:	170/407 - (41%)
Similarity:	230/407 - (56%)	Gaps:	62/407 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RSVFTLIAGLVVGYCLAQIFSSIAPHESLYPYLSRR-FS-DSQVATGG-------QLAPEQS--- 73
            ||.|  ..|.:||.|            |||..|.:. |: ||.....|       ::..|::
Zfish     7 RSAF--YVGFLVGTC------------SLYLLLRQAGFTRDSGSREPGTHDKTLLEMLEEENKNW 57

  Fly    74 --------GLKHDHR-NDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMS 129
                    .|.|.|. .::.::|:.|.|.|||||||||.|.|.:|||||||.||.:.|||::|:|
Zfish    58 KKERSALFNLNHPHHTGEDGALADSLYKRVRILCWVMTGPDNLEKKARHVKATWSRHCNIVVFIS 122

  Fly   130 SGADEELPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYN 194
            |..:.:.|||.|:..|||:.|:.|...||.||...|.::||:|.|||||||.:::|:|::|..::
Zfish   123 SVDNPDFPTVGLNTKEGRDQLYWKTIRAFHYVMEKHSDEADWFLKADDDTYVIVDNLRWILARHS 187

  Fly   195 PETPVHFGFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMEN 259
            ||.||:||.:|||:||||||||||||:||:|||||| |||. ..|:|...|.| ||:.:|:|||.
Zfish   188 PEDPVYFGRRFKPYVKQGYMSGGAGYVLSKEALRRF-VEGF-RTKVCTHTTSV-EDLAMGQCMEK 249

  Fly   260 LNVTAGDSRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPN 324
            :.|.||||||.:.|....||:||.|| .....|.||||||.||....|..||||||:|||||..:
Zfish   250 IGVKAGDSRDTMQRETFHPFVPESHL-TGTFPKTFWYWNYCYYPIVQGPQCCSDLAVSFHYVDAS 313

  Fly   325 SFYVLDYLIYHLKPYGLLRSLEPLPAKLKVGQFLPPPVEARGRLASNEDSADDYDRIYTTTTEKP 389
            ..|:|:|..|||:.:|.....:|....:|.    |..||.|                   ..|:.
Zfish   314 HMYLLEYYTYHLRAFGYKYRYQPPEPNVKA----PEKVETR-------------------VLEQK 355

  Fly   390 KEPDAREMDSKEVEKED 406
            .:.:|:|.:::..|..|
Zfish   356 DKVEAQEEENQSPELND 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245	5/22 (23%)
c1galt1b	NP_956345.1	Galactosyl_T	107..274	CDD:304462	91/169 (54%)
c1galt1b	NP_956345.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	355..374		4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3636
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H135611
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2547
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		mtm6507
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.930