DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and CG18558

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_608720.2	Gene:	CG18558 / 33482	FlyBaseID:	FBgn0031469	Length:	588	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	133/346 - (38%)
Similarity:	182/346 - (52%)	Gaps:	33/346 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NRSVFTLIAGLVV-GYCLAQ---IFSSIAPHESLYPYLSRRFSDSQVATGGQLAP------EQSG 74
            |.|..:...|.|: .||.|.   :...:..|  |.||             |.|.|      ....
  Fly   251 NHSWESCFGGAVLYPYCRAMQMYVLEFLLYH--LRPY-------------GHLTPLPELRSPNPL 300

  Fly    75 LKHDHRNDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSS--GAD-EEL 136
            .|...|..|..:|:.:.:.|||:|.|:|.|..:...||.:..|||:.||.:::..|  |.. ..|
  Fly   301 TKIASRPLNDQLAKMMYRSVRIICLVLTWPKKYMSGARAISETWGRHCNRVIYYGSFPGTTISGL 365

  Fly   137 PTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPETPVHF 201
            ..|.|:..:.|..||.|.|.||::.|.::.::.|:|||||||||||:||||.:|.||:|..|::|
  Fly   366 EIVGLNASDTRSKLWGKTKAAFRHAYRNYGHEVDWFYKADDDTYAVMENMRKLLKPYSPSNPIYF 430

  Fly   202 GFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNVTAGD 266
            |..|| .....||||||||:||:.|:....:....|   |.||....||..:|:|:..|.|.|||
  Fly   431 GSPFK-LGSTLYMSGGAGYVLSKSAVELLNLGAAEN---CQPGDQGTEDYVMGKCLSLLQVQAGD 491

  Fly   267 SRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPNSFYVLDY 331
            |||.:||.|.|....||.|||.:.|:.||...|||..|..||:|||..:||.|.|:|...:.|:.
  Fly   492 SRDLLGRQRFFSLSLEHFLIPNRDDEGFWLQEYLYQTTGTGLECCSTYSISIHNVSPYEMHFLET 556

  Fly   332 LIYHLKPYGLLRSLEPLPAKL 352
            ::|..:|||||....| |.:|
  Fly   557 ILYKRRPYGLLAGHAP-PRRL 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
CG18558	NP_608720.2	Galactosyl_T	<400..>458	CDD:304462	35/58 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D103727at6656
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850