DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and tgy

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001285425.1	Gene:	tgy / 32896	FlyBaseID:	FBgn0030984	Length:	373	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	148/369 - (40%)
Similarity:	207/369 - (56%)	Gaps:	31/369 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TSASLLSRSLLTEAPR-SKNRSV--FTLIAGLVVGYCLAQIFSSIAPHESLYPYLSRRFSDSQVA 63
            :|::.|:..:...|.| |.:|.|  ..|::..|:|               |:.|.     |..|.
  Fly    19 SSSNGLANGMYRSAQRISTDRLVLLILLVSTTVIG---------------LFAYW-----DVMVL 63

  Fly    64 TGGQLAPEQSGLKHDHRND---NVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNIL 125
            ..|.|...:.....|:...   |.::||::.:|||:||||:|.|..||.:|.||.||||||||.:
  Fly    64 NAGALPLSRGTSSVDYMEPGLRNETLAEKMHREVRVLCWVLTTPKYHKTRAIHVLRTWGKRCNKI 128

  Fly   126 LFMSSGADEELPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYML 190
            .||:|..|:|||||.|...:..|.||.|.||||.:::....::||:|.|||||||..:||:||||
  Fly   129 YFMTSEPDDELPTVVLTKPDRYEMLWGKTKEAFVHIHEQMRHEADWFIKADDDTYLFLENLRYML 193

  Fly   191 YPYNPETPVHFGFKFKPF----VKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDI 251
            |||:||||::|||.:|..    ..:.|||||:||:|||||||.| .||:.:...|.......||:
  Fly   194 YPYSPETPIYFGFNYKMVGTHQKNESYMSGGSGYVLSREALRIF-AEGVNDTTKCRQEDDHAEDV 257

  Fly   252 EIGRCMENLNVTAGDSRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAI 316
            |:|:|:.||.|.|||||||..|.|.:|..|...|:......:||.:.|.||.....:||.|:..:
  Fly   258 EMGKCLFNLGVKAGDSRDEQLRNRFYPIAPYGALLSGNVGMDFWLYKYAYYNPRSCMDCLSEYPV 322

  Fly   317 SFHYVAPNSFYVLDYLIYHLKPYGLLRSLEPLPAKLKVGQFLPP 360
            :||||.....||.||..|..:..|..:..|.||.|::..:.:.|
  Fly   323 AFHYVHSKQLYVYDYFNYQFQLSGRAQVAERLPKKIREEELVIP 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
tgy	NP_001285425.1	Galactosyl_T	103..>270	CDD:304462	87/167 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458873
Domainoid	1	1.000	173	1.000	Domainoid score	I3636
eggNOG	1	0.900	-	-		E1_KOG2246
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D103727at6656
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.800