DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and E03H4.3

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_493146.2	Gene:	E03H4.3 / 184018	WormBaseID:	WBGene00008471	Length:	322	Species:	Caenorhabditis elegans

Alignment Length:	294	Identity:	81/294 - (27%)
Similarity:	132/294 - (44%)	Gaps:	44/294 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 HESLYPYLSRRFSDSQVATGGQLAPEQSGLKHDHRNDNVSVAEQLKKEVRILCWVMTNPTNHKKK 110
            |:.|:|  ..|..|       :|.|   |::|.      :...:|....:|.|:|.|:...:..:
Worm    48 HQELFP--PTRSID-------KLIP---GIEHS------ASTLRLPNSGQIFCFVETSERYYNDR 94

  Fly   111 ARHVKRTWGKRCNILLFMSS----GADEELPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADF 171
            ...:..||.:||:...|.|.    .|:....||..::.:...:|:.|....|.|.|.|..|..|:
Worm    95 VPSIAATWLRRCDNGRFFSKTPLPSANMTYSTVYKNLEDSFFDLFRKSIFGFYYSYMHISNSFDW 159

  Fly   172 FYKADDDTYAVIENMRYMLYPYNPETPVHFGFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIP 236
            :.|||||||..::::|..|...:|..|::.|:..|..:|.||.|||||||||..|::.| ||.:.
Worm   160 YLKADDDTYFAMDHLREYLNTLDPSKPLYLGYVIKSGLKNGYNSGGAGYILSNAAVKIF-VEKLY 223

  Fly   237 NPKMCLPGTVVNEDIEIGRCMENLNVTAGDSRDEIGRGRMFPFIP-EHHLIPAKADKNFWYWNYL 300
            :.:...|.... ||..:|||:..:.:...|:||:.|..|..|:.| |...:.|.
Worm   224 HDEYGCPYDWA-EDRGMGRCLARVGIYPTDTRDDKGFNRFMPYRPSEQAAVEAG----------- 276

  Fly   301 YYKTDDGLDCCSDLAISFHYVAPNSFYVLDYLIY 334
                    ...|...:|.|....::..:||.|::
Worm   277 --------QFSSQKFVSLHRFPQDTMLLLDELLH 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
E03H4.3	NP_493146.2	Galactosyl_T	<130..252	CDD:304462	43/123 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.810