DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and c1galt1

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_002938761.1	Gene:	c1galt1 / 100487794	XenbaseID:	XB-GENE-992000	Length:	362	Species:	Xenopus tropicalis

Alignment Length:	345	Identity:	162/345 - (46%)
Similarity:	217/345 - (62%)	Gaps:	17/345 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 APRSKNRSVFTLIAGLVVGYCLAQIFSSI------APH---ESLYPYLSRRFSDSQVATGGQLAP 70
            ||.....|:.|...|:.:|:..:.:..||      :|.   |.|:.....|.||.  |..|....
Frog     2 APAKSVLSLATFSFGIAIGFIFSYVIFSIVFEGQDSPQGKPEVLHNDPHGRHSDD--APAGPPLQ 64

  Fly    71 EQSGLKHD---HRNDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSSGA 132
            .|.....|   |.:::..||:.|..:|:|||||||.|.|..||.:|||.||.:|||.:|:|||..
Frog    65 GQMDFNADAQQHHDEDTHVADDLYSKVKILCWVMTGPQNLDKKTKHVKATWAQRCNKVLYMSSEE 129

  Fly   133 DEELPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPET 197
            ::|.|||.||..|||:.|:.|..:||:||:.||..:||:|.|||||||.|::|:|::|..::|..
Frog   130 NKEFPTVGLDTKEGRDQLYWKTIKAFQYVHDHHLEEADWFMKADDDTYVVLDNLRWLLSKHDPND 194

  Fly   198 PVHFGFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNV 262
            ||:||.:|||:||||||||||||:||:|||:|||  .....:.|...:.| ||:.:|:||||:||
Frog   195 PVYFGRRFKPYVKQGYMSGGAGYVLSKEALKRFV--NAFKEEKCTHSSSV-EDLALGKCMENINV 256

  Fly   263 TAGDSRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPNSFY 327
            .||||||..|:....||:||||||.....|.||||||.||...:|..||||||:|||||...:.|
Frog   257 KAGDSRDTSGKETFHPFVPEHHLIHGYLPKTFWYWNYNYYPAVEGPGCCSDLAVSFHYVDSTTMY 321

  Fly   328 VLDYLIYHLKPYGLLRSLEP 347
            .|:||::||:|||......|
Frog   322 QLEYLVHHLRPYGYKHRYSP 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
c1galt1	XP_002938761.1	Galactosyl_T	<168..>254	CDD:389837	48/88 (55%)
c1galt1	XP_002938761.1	EEP	280..>361	CDD:382041	32/62 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3200
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2383
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		mtm9410
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070