DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8708 and LOC100486174

DIOPT Version :9

Sequence 1:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_002933748.2	Gene:	LOC100486174 / 100486174	-ID:	-	Length:	335	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	150/342 - (43%)
Similarity:	208/342 - (60%)	Gaps:	21/342 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSRSLLTEAPRSKNRSVFTLIAGLVVGYCLAQIFSSIAPHESLYPYLSRRFSDSQVATGGQLAPE 71
            :|:.|....|.|   |......||:||:     |.::..:.|:.. |:..|:...        |.
Frog     1 MSQKLTKNVPCS---SCLYFCLGLLVGF-----FMTLNMYNSVQE-LTISFNPPD--------PS 48

  Fly    72 QSGLKH-DHRNDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSSGADEE 135
            |....| .|.:||.:|:|.|.::||:|||:||:|.|.||||.|:||:|.:.|||.|||||.|:|.
Frog    49 QWDNNHFIHLSDNSNVSELLARKVRVLCWIMTSPKNLKKKAIHLKRSWARHCNITLFMSSTANEI 113

  Fly   136 LPTVKLDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPETPVH 200
            .||:.|...||||.|:.|...||:|::.::.:.||:|.|||||||.|:||::::|..|.||.|::
Frog   114 FPTIGLGTKEGREELYWKTIRAFQYIHQNYLDQADWFLKADDDTYVVMENLQFLLSNYTPEQPIY 178

  Fly   201 FGFKFKPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNVTAG 265
            .|.:|||||.||||||||||:||:|:|:|| ||.. ...:|...:.: ||:.:|:|||.|.|..|
Frog   179 LGKRFKPFVTQGYMSGGAGYVLSKESLKRF-VEAF-RTGVCTHTSSI-EDLALGQCMEKLGVIPG 240

  Fly   266 DSRDEIGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKTDDGLDCCSDLAISFHYVAPNSFYVLD 330
            ||||...|....||.||.|:.....:....||.|.||....|..||||||||||||:|...|:|:
Frog   241 DSRDSEKRETFHPFTPETHITSDYINDFDDYWTYCYYPIIQGPQCCSDLAISFHYVSPELMYMLE 305

  Fly   331 YLIYHLKPYGLLRSLEP 347
            |.:|:|:.||.....:|
Frog   306 YFVYYLRAYGYQYRYQP 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
LOC100486174	XP_002933748.2	Galactosyl_T	92..>237	CDD:304462	75/147 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I6207
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2383
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		mtm9410
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070