Protein Alignment Lpin and zgc:123305

DIOPT Version :10

• Sequence 1: NP_610359.2
• Gene: Lpin / 35790
• FlyBaseID: FBgn0263593
• Length: 1089
• Species: Drosophila melanogaster
• Sequence 2: XP_068077886.1
• Gene: zgc:123305 / 641489
• ZFINID: ZDB-GENE-051120-171
• Length: 1001
• Species: Danio rerio
• Alignment Length: 1064
• Identity: 374/1064 - (35%)
• Similarity: 528/1064 - (49%)
• Gaps: 184/1064 - (17%)

  Fly     7 VFSNFRDFYNDINAATLTGAIDVIVVEQRDGEFQCSPFHVRFGKLGVLRSREKVVDIEINGVPVD 71
            ||...::.|..:|.|||||.||||||.|.||.||||||||||||||||||:||||||||||.||.
Zfish    36 VFVTVKELYRGLNPATLTGGIDVIVVRQPDGSFQCSPFHVRFGKLGVLRSKEKVVDIEINGEPVS 100

  Fly    72 IQMKLGDSGEAFFVEECLEDEDEELPANLATSPIPNSF------------LASRDK-------AN 117
            :.|||||:|||||||| .||.:..:||:|.|||||...            .::|.|       .:
Zfish   101 LHMKLGDNGEAFFVEE-NEDFETRVPAHLCTSPIPTDVPEASEVTESQLSCSNRRKKRRRKRVRS 164

  Fly   118 DT--MEDISGVVTDKNA------SEELLLPLPLPRRNSIDFS-KEEPKEAVVEGSKFENQVSD-- 171
            ||  .||.|....:|.:      .||.|    |....||.:| .|||.|. ..|::..:..||
Zfish   165 DTHLHEDDSSSSDEKESLDPDALKEESL----LAASKSIYYSLSEEPYEE-ASGAREVHPHSDGE 224

  Fly   172 -------YTQRRHTDNTLERRNLSE--KLKEFTTQKIRQEWAEHEELFQGEKKPADSDSLDNQSK 227
                   |..|..:.     ::.||  |.:|....:::..|....::...|:  .:||||.::..
Zfish   225 CSLNESVYFSRPSSP-----KSDSELCKAQESLGPQMQWNWGAFPKVCPSER--VESDSLTHELP 282

  Fly   228 ASNEAETEKAIPAVIEDTEKEKDQ---------IKPDVNLTTVTTSEATKEVSKSKTKKRRKKSQ 283
            :............:...|..:.|.         ::|:..:.||:...:.:.|..|
Zfish   283 SPITPSDHSHFRTIHRQTSVDIDSTDSAVTVTVVRPEPQIGTVSPVSSDEAVCSS---------- 337

  Fly   284 MKKNAQRKNSSSSSLGSAGGGDLPSAETPSLGVSNIDE--GDAPISSATNNNNTSSSNDEQLSAP 346
              .|.|.....:::|.|.  .|..|.....|...:..|  .:..|.:.|:..||.:.::
Zfish   338 --INTQLNVKFTNTLQSP--DDCFSQSWSGLENKHSQEIIAEKEIETMTSCGNTVNESN------ 392

  Fly   347 LVTARTGDDSPLSEIPHTPTSNPRLDLDIHFFSDTEITTPVGGGGAGSGRAAGGRPSTPIQSDSE 411
                   :|:.|..:.|           :...|:..|...:          ..|..:..:::::|
Zfish   393 -------NDASLDSVAH-----------LENCSENNIVRTI----------TFGESNQDLKAEAE 429

  Fly   412 LETTM----RDNRHVVT---EESTASWKWGELPTPEQAKNEAMSAAQ--VQQSEHQSMLSNMFSF 467
            |.:.:    :.:..::|   .||........|||.:.|.:..::.:|  :.|||..::|....|.
Zfish   430 LNSILLPKHQSSVEILTLRASESEEGAGLETLPTNQNADSAGVTGSQEIIVQSEDPTVLEASKSA 494

  Fly   468 MKRANR-LRKEKGVGEVGDIYLSDLDAGSMDPEMAALYFPSPLSKAASPPEEDGESGNGTSLPHS 531
            ..:..| :::...:|. .||||.||  .|:|||:||||||...::::......|...:..|...|
Zfish   495 DSQDKRKVKRSHHLGP-SDIYLDDL--SSLDPEVAALYFPKSEAESSDLRSSHGPDPSPPSGQMS 556

  Fly   532 PSSLEEGQKSIDSD----FDETKQQRDNNRYLDFVAMSMCGMSEQGAPPSDEEFDRHLVNYPDVC 592
            |.|  :|..:.||.    .|.|....|       |.||:||..:. :..|.|:|..|||.:.|..
Zfish   557 PQS--QGSANADSGTEYLSDSTSDSLD-------VTMSLCGRGDI-SQISKEKFMEHLVKFQDFV 611

  Fly   593 KSPSIFSSPNLVVRLNGKYYTWMAACPIVMTMITFQKPLTHDAIEQLMSQTVDGKCLPGDEKQEA 657
            .:|.|...||||:.:|.|||.|..|.|:::::..|||.|....||||:...:..|
Zfish   612 NNPGIIEDPNLVICINSKYYNWAVAAPMILSVQAFQKTLPKSTIEQLVKDKMPKK---------- 666

  Fly   658 VAQADNGGQTKRYWWSWRRSQDAAPNHLNNTHGMPLGKDEKDGDQAAVATQTSRPTSPDITDP-T 721
                     :.|:|:||||..      |||..|.|          .|.|.::....|..:..| |
Zfish   667 ---------SGRWWFSWRRKD------LNNIPGNP----------KAGAEESQLEASASVAGPST 706

  Fly   722 LSKSDSLVNAENTSALVDNLEELTMASNKSDEPKERYKKSLRLSSAAIKKLNLKEGMNEIEFSVT 786
            |..|..|.:.|:.|..|....||   .|.:....:.|:|||||:|..|:.|||:||.|::.||||
Zfish   707 LKSSVELSSDEDGSVSVRKNTEL---MNTAQCISQMYRKSLRLTSEQIESLNLREGANKVVFSVT 768

  Fly   787 TAYQGTTRCKCYLFRWKHNDKVVISDIDGTITKSDVLGHILPMVGKDWAQLGVAQLFSKIEQNGY 851
            |.||||.||:..::.|.::||::||||||||||||.||||||.:||||...|:|:|:.||.||||
Zfish   769 TQYQGTCRCEAAIYLWSYDDKIIISDIDGTITKSDALGHILPQLGKDWTHHGIAKLYHKIHQNGY 833

  Fly   852 KLLYLSARAIGQSRVTREYLRSIRQGNVMLPDGPLLLNPTSLISAFHREVIEKKPEQFKIACLSD 916
            |.||.||||||.:.:|:.||:.:.....:||.||:||.|:||.||.||||||||||.||||||:|
Zfish   834 KFLYCSARAIGMADITKGYLQWVNDRGTVLPKGPVLLAPSSLFSALHREVIEKKPEVFKIACLTD 898

  Fly   917 IRDLFPD-KEPFYAGYGNRINDVWAYRAVGIPIMRIFTINTKGELKHELTQTFQSSGYINQSLEV 980
            |||||.. .:||||.:|||.||.:||:.||:|...|||:|.||||..|.|:..:|| |.:.|..|
Zfish   899 IRDLFSSVTQPFYAAFGNRTNDAYAYKEVGVPETHIFTVNPKGELIREKTKGNKSS-YSHLSELV 962

  Fly   981 DEYFPLLTNQDEFDYRTDIFDDEE 1004
            |.:|||:..     :.|..||..|
Zfish   963 DHFFPLICK-----HPTTSFDCPE 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lpin	NP_610359.2	Lipin_N	1..104	CDD:461356	67/96 (70%)
		Lipin_mid	562..674	CDD:465292	36/111 (32%)
		LNS2	760..985	CDD:462403	133/225 (59%)
zgc:123305	XP_068077886.1	Lipin_N	26..132	CDD:461356	67/96 (70%)
		Lipin_mid	582..674	CDD:465292	36/111 (32%)
		LNS2	742..967	CDD:462403	133/225 (59%)
		WRNPLPNID	980..>1000	CDD:464448	1/2 (50%)