DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pabp2 and PABN1

DIOPT Version :9

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001190511.1	Gene:	PABN1 / 835186	AraportID:	AT5G51120	Length:	265	Species:	Arabidopsis thaliana

Alignment Length:	257	Identity:	95/257 - (36%)
Similarity:	129/257 - (50%)	Gaps:	76/257 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EETNGEQETEIATEVEEE--------GSMQIDP-----ELEAIKARVKEMEEEAEKIKQMQSEVD 69
            ||..||.:||   |.||.        |..:::|     :||.:|.|:||:||||..:::||::.:
plant    18 EEEEGEMDTE---EYEEHGGEEGAAAGDEELEPGSSSRDLEDMKKRIKEIEEEAGALREMQAKAE 79

  Fly    70 KQMAGGSTTGLATVPL-------------------------------------SLEEKQEIDTRS 97
            |.|  |::.||..|.|                                     |..||:|:|:||
plant    80 KDM--GASQGLKLVLLIMILLWVYILESFSESMNLSRNLLEFEYEKEIINSGVSAAEKEEVDSRS 142

  Fly    98 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFR 162
            :|||||||..:.||::.||..|||:||||||.:|. |.||||||:||...|.|:.:|.:||:...
plant   143 IYVGNVDYACTPEEVQQHFQSCGTVNRVTILTDKF-GQPKGFAYVEFVEVEAVQNSLILNESELH 206

  Fly   163 GRQIKVMSKRTNRPGLSTTNRFARGSFRGRGARVSRACCHSTFRGARRAMGYRGRANYYAPY 224
            ||||||.:||||.||:.        .|||||            |..|...|:.....:|.||
plant   207 GRQIKVSAKRTNVPGMR--------QFRGRG------------RPFRPMRGFMPGVPFYPPY 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	67/165 (41%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:240994	42/74 (57%)
PABN1	NP_001190511.1	RRM	<101..>265	CDD:223796	65/169 (38%)
PABN1	NP_001190511.1	RRM_II_PABPs	142..213	CDD:240752	41/71 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	86	1.000	Domainoid score	I2786
eggNOG	1	0.900	-	-		E1_KOG4209
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	150	1.000	Inparanoid score	I1715
OMA	1	1.010	-	-		QHG53866
OrthoDB	1	1.010	-	-		D1412946at2759
OrthoFinder	1	1.000	-	-		FOG0001228
OrthoInspector	1	1.000	-	-		otm2915
orthoMCL	1	0.900	-	-		OOG6_101686
Panther	1	1.100	-	-	O	PTHR23236
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X689
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840