Protein Alignment Pabp2 and SNRNP70

DIOPT Version :10

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_003080.2
• Gene: SNRNP70 / 6625
• HGNCID: 11150
• Length: 437
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 44/184 - (23%)
• Similarity: 79/184 - (42%)
• Gaps: 21/184 - (11%)

  Fly    14 LESL--EETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEME-EEAEKIKQMQSEVDKQMAGG 75
            ||.|  |:.:.:....||..:.|....:..|.....:.|.:.|| :..|||::.|.||:.::...
Human    25 LEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMW 89

  Fly    76 STTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFA 140
            .       |.:....|....::::|..|:|..:..:|...|...|.|.|:.::.:|..|.|:|:|
Human    90 D-------PHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYA 147

  Fly   141 YIEFGSKEFVETALAMNE-----------TLFRGRQIKVMSKRTNRPGLSTTNR 183
            :||:..:..:.:|....:           .:.|||.:|....|....||..|.|
Human   148 FIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRR 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	15/56 (27%)
		RRM_II_PABPN1	97..172	CDD:409966	20/85 (24%)
SNRNP70	NP_003080.2	U1snRNP70_N	3..94	CDD:432406	18/75 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..79		7/30 (23%)
		Required for interaction with U1 RNA. /evidence=ECO:0000269|PubMed:2467746	92..202		26/110 (24%)
		RRM_snRNP70	102..187	CDD:409682	20/84 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..437		5/15 (33%)