Protein Alignment Pabp2 and HNRNPA1L3

DIOPT Version :10

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001383170.1
• Gene: HNRNPA1L3 / 642659
• HGNCID: 48778
• Length: 320
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 40/200 - (20%)
• Similarity: 70/200 - (35%)
• Gaps: 50/200 - (25%)

  Fly    46 AIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAE 110
            |:.||..:::....:.|:..|..|.|......|                .:.::||.:.......
Human    71 AMNARPHKVDGRVVEPKRAVSREDSQRPDAHLT----------------VKKIFVGGIKEDTEEH 119

  Fly   111 ELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQI---KVMSKR 172
            .|..:|...|.|..:.|:.::..|..:|||::.|...:.|:..:........|...   |.:||:
Human   120 HLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQ 184

  Fly   173 ------TNRPGLSTTNRFA---------------RGSFRGRGARVSRACCHSTFRGARRAMGYRG 216
                  :::.|.|.:..|.               .|:|.|||.          |.|:|...||.|
Human   185 EMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGG----------FGGSRGGGGYGG 239

  Fly   217 RANYY 221
            ..:.|
Human   240 SGDGY 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	5/21 (24%)
		RRM_II_PABPN1	97..172	CDD:409966	16/77 (21%)
HNRNPA1L3	NP_001383170.1	RRM1_hnRNPA1	12..92	CDD:410154	4/20 (20%)
		RRM2_hnRNPA3	105..184	CDD:409996	16/78 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..218		5/35 (14%)
		HnRNPA1	255..292	CDD:463312
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..320