DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pabp2 and pabpn1l

DIOPT Version :9

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001016352.1	Gene:	pabpn1l / 549106	XenbaseID:	XB-GENE-1000600	Length:	218	Species:	Xenopus tropicalis

Alignment Length:	217	Identity:	107/217 - (49%)
Similarity:	141/217 - (64%)	Gaps:	33/217 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SLEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQSE------------- 67
            ||::.:|.:|.::.           ||||:||:.||:|||||||::|.:..|
Frog    10 SLDKGDGAEECDLD-----------DPELKAIRMRVREMEEEAERLKGLSGEDKSIGVSSRPCMK 63

  Fly    68 -VDKQMAGGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNK 131
             :..:|..|:.|.....|||.|||:|||.|||||||||||.:|::|||||..||:|||:||||:|
Frog    64 LIHSKMTAGAYTEGPPRPLSAEEKKEIDKRSVYVGNVDYGGTAQDLEAHFSSCGSINRITILCDK 128

  Fly   132 ADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNRFARGSFRGRGARV 196
            ..|||||:|||||..:..|:.|:||:||:||||.|||:.||||.||:|||:   ||.|||| .|.
Frog   129 FSGHPKGYAYIEFAERNSVDVAVAMDETVFRGRTIKVLPKRTNMPGISTTD---RGGFRGR-PRG 189

  Fly   197 SRACCHSTFRGAR-RAMGYRGR 217
            :|.   :..||.| |...:|||
Frog   190 NRG---NYQRGQRPRGRPFRGR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	77/142 (54%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:240994	49/74 (66%)
pabpn1l	NP_001016352.1	RRM_II_PABPN1L	94..170	CDD:240995	50/75 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412946at2759
OrthoFinder	1	1.000	-	-		FOG0001228
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X689
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010