Protein Alignment Pabp2 and MSI1

DIOPT Version :10

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 37/171 - (21%)
• Similarity: 67/171 - (39%)
• Gaps: 26/171 - (15%)

  Fly    65 QSEVDKQMA-------GGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTI 122
            |:.|||.:|       ..:.......|...:.|....|:.::||.:....:.|:::.:|...|.:
Human    71 QAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKV 135

  Fly   123 NRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQI---KVMSKRTNRPGLSTTNRF 184
            :...::.:|.....:||.::.|.|::.||....::......:.:   |...|....|
Human   136 DDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSP-------- 192

  Fly   185 ARGSFRGRGARVSRACCH--STFRGARRAMGYRG-RANYYA 222
             .||.|||    ||...:  ..|......:||.| :|..||
Human   193 -TGSARGR----SRVMPYGMDAFMLGIGMLGYPGFQATTYA 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	1/2 (50%)
		RRM_II_PABPN1	97..172	CDD:409966	13/77 (17%)
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	5/24 (21%)
		PABP-1234	<32..339	CDD:130689	37/171 (22%)
		RRM2_MSI	110..183	CDD:240769	12/72 (17%)