DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pabp2 and CG6937

DIOPT Version :9

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_651066.2	Gene:	CG6937 / 42662	FlyBaseID:	FBgn0038989	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	157	Identity:	34/157 - (21%)
Similarity:	64/157 - (40%)	Gaps:	34/157 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KARVKEMEEEAEKIK-----------QMQSEVDK---QMAGGSTTGLATVPLSLEEKQEIDTRSV 98
            |.:.:::|:::...|           |::.:|.|   |...|...|:                 |
  Fly     6 KPKAQKIEKQSTPKKPIDAAKNVVSGQLKKKVTKARPQKPKGPERGV-----------------V 53

  Fly    99 YVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRG 163
            .|.::.:|...::|..:|...|.:.||.:..:...|:.||:|::||   |:.|.|....:|:...
  Fly    54 IVKHLPHGFFEQQLRQYFRQFGRVLRVRLARSLRTGNSKGYAFVEF---EYPEVAKVAADTMDNY 115

  Fly   164 RQIKVMSKRTNRPGLSTTNRFARGSFR 190
            ...:.:.|.|..|....|..|.|.|.:
  Fly   116 LMFQKVVKATYIPPEKQTLNFFRTSLK 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	27/137 (20%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:240994	18/74 (24%)
CG6937	NP_651066.2	RRM	<32..>170	CDD:223796	31/131 (24%)
		RRM_NIFK_like	52..125	CDD:240753	19/92 (21%)
		Upf2	253..>304	CDD:281974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930