Protein Alignment Pabp2 and RBM34

DIOPT Version :10

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_055829.2
• Gene: RBM34 / 23029
• HGNCID: 28965
• Length: 430
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 59/209 - (28%)
• Similarity: 92/209 - (44%)
• Gaps: 33/209 - (15%)

  Fly     6 ITLNEDQLLESLEETNGEQETEIATEVEEEGSM---------QIDPELEAIKARVKEMEEEAEKI 61
            :|.|:.:|....:|....:.....:.:..||::         :|.|:.:.|.|.|...||.|  .
Human   194 VTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKEESA--A 256

  Fly    62 KQMQSEVDKQMAGGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVT 126
            .|.......|:|.|..   ..|.|:.|.... |.|||:|||:.|......:|.||..||:|..|.
Human   257 TQALKRNGAQIADGFR---IRVDLASETSSR-DKRSVFVGNLPYKVEESAIEKHFLDCGSIMAVR 317

  Fly   127 ILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMS----------------KRTNR 175
            |:.:|..|..|||.|:.|.:.:.|..||.:|.:...||:::||.                |..::
Human   318 IVRDKMTGIGKGFGYVLFENTDSVHLALKLNNSELMGRKLRVMRSVNKEKFKQQNSNPRLKNVSK 382

  Fly   176 P--GLSTTNRFARG 187
            |  ||:.|::.|.|
Human   383 PKQGLNFTSKTAEG 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	15/70 (21%)
		RRM_II_PABPN1	97..172	CDD:409966	29/90 (32%)
RBM34	NP_055829.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..123
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..153
		RRM1_RBM34	185..276	CDD:409828	18/86 (21%)
		RRM2_RBM34	288..360	CDD:409829	27/71 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	365..395		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	411..430