DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pabp2 and EEED8.12

DIOPT Version :9

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_495021.1	Gene:	EEED8.12 / 173922	WormBaseID:	WBGene00017140	Length:	197	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	79/204 - (38%)
Similarity:	108/204 - (52%)	Gaps:	33/204 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EEGSMQIDPELEAIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTGLATVPLSLEEKQEIDTRSV 98
            ||.|...:.|:||          |:..::|:|:::.|.:...     |.||.:.||::.||.:||
Worm    14 EESSNSFEMEIEA----------ESAILEQIQNKMAKNLESA-----AYVPPTEEEQKAIDAKSV 63

  Fly    99 YVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRG 163
            ::||||:.::.||:|.||.|||.|.|.||..:|.....|.||||||.....:|.||.||.:|||.
Worm    64 FIGNVDFNSTIEEVEEHFKGCGHIVRTTIPKDKFTKKQKNFAYIEFDDSSSIENALVMNGSLFRS 128

  Fly   164 RQIKVMSKRTNRPGLSTTNR-FARGSF-RGRGAR-----------VSRACCHSTFRGARRAMGYR 215
            |.|.|.:||||.||:....| .:||:| |||||.           |.....:...||.|   |.|
Worm   129 RPIVVTAKRTNIPGMGHGVRGSSRGTFGRGRGAARGAPGRQQTVVVKYVYVNGPNRGGR---GGR 190

  Fly   216 GRANYYAPY 224
            ||.  :.||
Worm   191 GRR--FNPY 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	51/128 (40%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:240994	37/74 (50%)
EEED8.12	NP_495021.1	RRM	<11..>133	CDD:223796	53/133 (40%)
EEED8.12	NP_495021.1	RRM_II_PABPs	62..134	CDD:240752	36/71 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4209
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53866
OrthoDB	1	1.010	-	-		D1412946at2759
OrthoFinder	1	1.000	-	-		FOG0001228
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23236
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X689
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930