DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pabp2 and pabp-2

DIOPT Version :9

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_492504.1	Gene:	pabp-2 / 172768	WormBaseID:	WBGene00003904	Length:	205	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	106/239 - (44%)
Similarity:	141/239 - (58%)	Gaps:	49/239 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADEDITLNEDQLLESLEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQ 65
            |:|.|| :::|.|  ::|:..|:                 |.:|.||:..:.|:|||.:|:|.:|
Worm     1 MSDNDI-IDDDVL--NIEDMTGD-----------------DADLSAIEGDLNEIEEEQKKLKAIQ 45

  Fly    66 SEVDKQMAG------GSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINR 124
            :|    |.|      .|.:..:...|:.|||.|.|.:|||||||||||:|||:|.||||||:::|
Worm    46 NE----MVGHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSR 106

  Fly   125 VTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNRFARGSF 189
            |||.|::..||||||||:||..||.::.||||.::|.|||||||..||||:||:||||   |..|
Worm   107 VTIQCDRFSGHPKGFAYVEFTEKEGMQNALAMTDSLLRGRQIKVDPKRTNKPGMSTTN---RPPF 168

  Fly   190 RGRGAR---------VSRACCHSTFRGARRAMGYRGRANYYAPY 224
            ||||.|         |.........|||||..|       :|||
Worm   169 RGRGGRGRGNVIVKYVYAGGFRPRGRGARRRPG-------FAPY 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	70/134 (52%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:240994	50/74 (68%)
pabp-2	NP_492504.1	RRM_SF	79..154	CDD:388407	50/74 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161304
Domainoid	1	1.000	110	1.000	Domainoid score	I3961
eggNOG	1	0.900	-	-		E1_KOG4209
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3412
Inparanoid	1	1.050	171	1.000	Inparanoid score	I2751
Isobase	1	0.950	-	0	Normalized mean entropy	S1069
OMA	1	1.010	-	-		QHG53866
OrthoDB	1	1.010	-	-		D1412946at2759
OrthoFinder	1	1.000	-	-		FOG0001228
OrthoInspector	1	1.000	-	-		oto19589
orthoMCL	1	0.900	-	-		OOG6_101686
Panther	1	1.100	-	-	LDO	PTHR23236
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4120
SonicParanoid	1	1.000	-	-		X689
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790