DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pabp2 and HNRNPA1L2

DIOPT Version :10

Sequence 1:	NP_476902.1	Gene:	Pabp2 / 35788	FlyBaseID:	FBgn0005648	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001011724.1	Gene:	HNRNPA1L2 / 144983	HGNCID:	27067	Length:	320	Species:	Homo sapiens

Alignment Length:	35	Identity:	9/35 - (25%)
Similarity:	15/35 - (42%)	Gaps:	6/35 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SQALPQPEEAAAASSTNTDGASANTQLVLELTPEE 53
            |:.:|..|:      .|.|....|.::|:.|...|
Human    41 SRIIPSTED------PNEDIVERNIRIVVPLNNRE 69

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	9/35 (26%)
Pabp2	NP_476902.1	RRM_II_PABPN1	97..172	CDD:409966
HNRNPA1L2	NP_001011724.1	Globular A domain	4..94		9/35 (26%)
		RRM1_hnRNPA1	12..92	CDD:410154	9/35 (26%)
		Globular B domain	95..185
		RRM_SF	105..184	CDD:473069
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..216
		RNA-binding RGG-box	218..240
		HnRNPA1	255..292	CDD:463312
		Nuclear targeting sequence. /evidence=ECO:0000250	268..305
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..320
Blue background indicates that the domain is not in the aligned region.

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