Protein Alignment Pabp2 and BCL2L2-PABPN1

DIOPT Version :9

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001374269.1
• Gene: BCL2L2-PABPN1 / 100529063
• HGNCID: 42959
• Length: 372
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 129/231 - (55%)
• Similarity: 158/231 - (68%)
• Gaps: 14/231 - (6%)

  Fly     4 EDITLNEDQLLES---LEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQ 65
            |...|..|..||.   |.|.|......:.|.....|::    |||||||||:||||||||:|::|
Human   146 EFTALYGDGALEEARRLREGNWASVRTVLTGAVALGAL----ELEAIKARVREMEEEAEKLKELQ 206

  Fly    66 SEVDKQMAGGSTTGLA-TVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILC 129
            :||:|||......|.| .|.:|:|||.|.|.||:|||||||||:||||||||||||::|||||||
Human   207 NEVEKQMNMSPPPGNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILC 271

  Fly   130 NKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNR-FARGSFRGRG 193
            :|..|||||||||||..||.|.|:||::|:|||||||||:.|||||||:|||:| |.|..:|.|.
Human   272 DKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRGFPRARYRART 336

  Fly   194 ARV--SRACCHSTFRGARRAMGYRGRA---NYYAPY 224
            ...  ||:..:|.|....|...|||||   ::|:||
Human   337 TNYNSSRSRFYSGFNSRPRGRVYRGRARATSWYSPY 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	RRM	<43..>172	CDD:223796	91/129 (71%)
		RRM_II_PABPN1	97..172	CDD:240994	57/74 (77%)
BCL2L2-PABPN1	NP_001374269.1	bcl-2	11..185	CDD:273308	10/42 (24%)
		RRM_II_PABPN1	239..314	CDD:409966	57/74 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412946at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101686
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.800