Protein Alignment Pabp2 and BCL2L2-PABPN1

DIOPT Version :10

• Sequence 1: NP_476902.1
• Gene: Pabp2 / 35788
• FlyBaseID: FBgn0005648
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001374269.1
• Gene: BCL2L2-PABPN1 / 100529063
• HGNCID: 42959
• Length: 372
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 129/231 - (55%)
• Similarity: 158/231 - (68%)
• Gaps: 14/231 - (6%)

  Fly     4 EDITLNEDQLLES---LEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQ 65
            |...|..|..||.   |.|.|......:.|.....|::    |||||||||:||||||||:|::|
Human   146 EFTALYGDGALEEARRLREGNWASVRTVLTGAVALGAL----ELEAIKARVREMEEEAEKLKELQ 206

  Fly    66 SEVDKQMAGGSTTGLA-TVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILC 129
            :||:|||......|.| .|.:|:|||.|.|.||:|||||||||:||||||||||||::|||||||
Human   207 NEVEKQMNMSPPPGNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILC 271

  Fly   130 NKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNR-FARGSFRGRG 193
            :|..|||||||||||..||.|.|:||::|:|||||||||:.|||||||:|||:| |.|..:|.|.
Human   272 DKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGISTTDRGFPRARYRART 336

  Fly   194 ARV--SRACCHSTFRGARRAMGYRGRA---NYYAPY 224
            ...  ||:..:|.|....|...|||||   ::|:||
Human   337 TNYNSSRSRFYSGFNSRPRGRVYRGRARATSWYSPY 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pabp2	NP_476902.1	DNA_pol_phi	<3..68	CDD:461488	29/66 (44%)
		RRM_II_PABPN1	97..172	CDD:409966	57/74 (77%)
BCL2L2-PABPN1	NP_001374269.1	bcl-2	11..185	CDD:273308	10/42 (24%)
		RRM_II_PABPN1	239..314	CDD:409966	57/74 (77%)